Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032977 | 0.93 | MEN1 (0.38) | KMT2AMEN1TP53ALOX15ALDH1A1 | |
| SCHEMBL1709409 | 0.85 | POLB (0.38) | KMT2AMEN1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL1709490 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TDP1MAPTMGLL | |
| SCHEMBL1709474 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TDP1MAPTMGLL | |
| SCHEMBL1709397 | 0.82 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1RAB9ATDP1 | |
| SCHEMBL1709384 | 0.80 | SIGMAR1 (0.40) | KMT2AMEN1TP53ALOX15ALDH1A1 | |
| SCHEMBL10033003 | 0.79 | EPHX2 (0.45) | KMT2AALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL10033001 | 0.79 | NPC1 (0.38) | KMT2AMEN1TP53ALDH1A1POLB | |
| SCHEMBL10033134 | 0.79 | USP30 (0.36) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1709410 | 0.78 | POLB (0.35) | KMT2AMEN1TP53POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |