Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709497 | 0.90 | EPHX2 (0.43) | EPHX2POLBALDH1A1KMT2APTGES | |
| SCHEMBL10033001 | 0.89 | NPC1 (0.38) | POLBALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1709398 | 0.87 | KDM1A (0.36) | KMT2ANPC1RAB9A | |
| SCHEMBL10033134 | 0.85 | USP30 (0.36) | ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10033135 | 0.81 | KCNN4 (0.38) | EPHX2ALDH1A1 | |
| SCHEMBL1709374 | 0.79 | KMT2A (0.39) | POLBALDH1A1KMT2AKLK7MAPT | |
| SCHEMBL10033109 | 0.77 | KDM1A (0.41) | EPHX2POLBALDH1A1KMT2AMAPT | |
| SCHEMBL1709408 | 0.77 | DGAT1 (0.38) | — | |
| SCHEMBL1709399 | 0.76 | PTGDR (0.41) | EPHX2POLBALDH1A1KMT2ANPC1 | |
| SCHEMBL1709407 | 0.76 | TP53 (0.39) | EPHX2ALDH1A1KMT2APTGESSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |