Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033135 | 0.90 | KCNN4 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1709359 | 0.88 | USP30 (0.38) | USP30HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10033001 | 0.87 | NPC1 (0.38) | PTGDR2PTGDRALDH1A1NPC1RAB9A | |
| SCHEMBL10033003 | 0.85 | EPHX2 (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1709399 | 0.83 | PTGDR (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1709398 | 0.82 | KDM1A (0.36) | USP30HDAC1HDAC8HDAC6GRIA4 | |
| SCHEMBL10033177 | 0.81 | GRIA4 (0.38) | USP30HDAC6GRIA4DGAT1SOAT1 | |
| SCHEMBL1709358 | 0.79 | DPEP1 (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2DGAT1 | |
| SCHEMBL1709459 | 0.79 | CXCR3 (0.34) | PTGDRNPC1RAB9A | |
| SCHEMBL1709374 | 0.79 | KMT2A (0.39) | L3MBTL1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |