SCHEMBL17101341

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18075896	0.86	SIGMAR1 (0.48)	SIGMAR1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL17113644	0.80	OPRM1 (0.50)	SIGMAR1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL17101486	0.79	OPRL1 (0.46)	SIGMAR1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL13864847	0.73	OPRL1 (0.48)	SIGMAR1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL14136159	0.72	OPRL1 (0.47)	SIGMAR1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL1488906	0.69	GAA (0.50)	SIGMAR1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL2604320	0.69	TSHR (0.75)	SIGMAR1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL8364002	0.69	HSD11B1 (0.61)	SIGMAR1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL17101329	0.69	SIGMAR1 (0.50)	SIGMAR1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL4462811	0.68	OPRM1 (0.46)	SIGMAR1OPRM1OPRD1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.