Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 3/20 | 0.58 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.58 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.58 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | PYGB | P11216 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| B-D-Galactose SCHEMBL9880688 | 1.00 | LGALS3 (0.58) | LGALS3LGALS1LGALS9LGALS8CA12 | |
| B-D-Galactose SCHEMBL10050866 | 1.00 | LGALS3 (0.58) | LGALS3LGALS1LGALS9LGALS8CA12 | |
| B-D-Galactose SCHEMBL2441804 | 1.00 | LGALS3 (0.58) | LGALS3LGALS1LGALS9LGALS8CA12 | |
| B-D-Galactose SCHEMBL13220216 | 1.00 | LGALS3 (0.58) | LGALS3LGALS1LGALS9LGALS8CA12 | |
| B-D-Galactose SCHEMBL18649521 | 1.00 | LGALS3 (0.58) | LGALS3LGALS1LGALS9LGALS8CA12 | |
| B-D-Galactose SCHEMBL8527882 | 1.00 | LGALS3 (0.58) | LGALS3LGALS1LGALS9LGALS8CA12 | |
| B-D-Galactose SCHEMBL23758905 | 1.00 | LGALS3 (0.58) | LGALS3LGALS1LGALS9LGALS8CA12 | |
| B-D-Galactose SCHEMBL79549 | 1.00 | LGALS3 (0.58) | LGALS3LGALS1LGALS9LGALS8CA12 | |
| B-D-Galactose SCHEMBL21123450 | 1.00 | LGALS3 (0.58) | LGALS3LGALS1LGALS9LGALS8CA12 | |
| B-D-Galactose SCHEMBL9820102 | 1.00 | LGALS3 (0.58) | LGALS3LGALS1LGALS9LGALS8CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230178-A1 | TRIOXACARCIN ANALOGS AND DIMERS AS POTENT ANTICANCER AGENTS | WILLIAM MARSH RICE UNIVERSITY (US) | 2021-07-29 | — | — | US | disclosed |
| US-10781183-B2 | Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-09-22 | — | — | US | disclosed |
| US-20190308942-A1 | SMALL MOLECULE INDUCERS OF REACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-10-10 | — | — | US | disclosed |
| EP-3122376-A1 | METABOLICALLY-ACTIVATED DRUG CONJUGATES TO OVERCOME RESISTANCE IN CANCER THERAPY | The Brigham and Women's Hospital, Inc. (US) | 2017-02-01 | — | — | EP | disclosed |
| WO-2015149001-A1 | METABOLICALLY-ACTIVATED DRUG CONJUGATES TO OVERCOME RESISTANCE IN CANCER THERAPY | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190308942-A1 | SMALL MOLECULE INDUCERS OF REACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY | SQOR, MAVS, TFAM | LGALS3 2588/4885LGALS1 3068/4885LGALS9 3365/4885 |
| US-20210230178-A1 | TRIOXACARCIN ANALOGS AND DIMERS AS POTENT ANTICANCER AGENTS | ANXA5, HCCS, BAX | LGALS3 2628/4885LGALS1 2491/4885LGALS9 1516/4885 |
| US-10781183-B2 | Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity | SQOR, MAVS, TFAM | LGALS3 2588/4885LGALS1 3068/4885LGALS9 3365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.