Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534329 | 0.71 | CA1 (0.54) | MAPTCYP3A4 | |
| SCHEMBL13184538 | 0.71 | KDM4E (0.59) | ADRB2MAPTALDH1A1LOXL2NCF1 | |
| SCHEMBL21664123 | 0.71 | ALDH1A1 (0.47) | MGLLMAPTALDH1A1ATMLMNA | |
| SCHEMBL20411019 | 0.71 | ALDH1A1 (0.43) | MGLLMAPTALDH1A1ATMLMNA | |
| SCHEMBL8378973 | 0.71 | MGLL (0.43) | MGLLMAPTALDH1A1ATMLMNA | |
| SCHEMBL21663870 | 0.69 | MAPT (0.48) | MGLLMAPTALDH1A1ATMKDM4E | |
| SCHEMBL2504209 | 0.68 | KDM4E (0.68) | ADRB2MAPTLOXL2NCF1KDM4E | |
| SCHEMBL9608569 | 0.67 | ALDH1A1 (0.40) | MGLLMAPTALDH1A1ATMLMNA | |
| SCHEMBL22057583 | 0.67 | MAPT (0.47) | MGLLMAPTALDH1A1ATMLMNA | |
| SCHEMBL2242209 | 0.67 | NISCH (0.68) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435019-B1 | DODECA-2E,4E-DIENE AMIDES AND THEIR USE AS MEDICAMENTS AND COSMETICS | WOLFF AUGUST GMBH & CO KG ARZNEIMITTEL DR (DE) | 2015-09-23 | — | — | EP | disclosed |