Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21664123 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTATMLMNASMN1; SMN2 | |
| SCHEMBL27489704 | 0.74 | SMN1; SMN2 (0.43) | ALDH1A1MAPTATMLMNASMN1; SMN2 | |
| SCHEMBL27886244 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MAPTATMLMNASMN1; SMN2 | |
| SCHEMBL21663870 | 0.72 | MAPT (0.48) | ALDH1A1MAPTATMLMNASMN1; SMN2 | |
| SCHEMBL27504564 | 0.68 | LMNA (0.44) | ALDH1A1MAPTATMLMNASMN1; SMN2 | |
| SCHEMBL17115185 | 0.67 | ADRB2 (0.45) | ALDH1A1MAPTATMLMNASMN1; SMN2 | |
| SCHEMBL14875049 | 0.67 | ALDH1A1 (0.38) | ALDH1A1MAPTATMLMNASMN1; SMN2 | |
| SCHEMBL14875079 | 0.67 | LMNA (0.40) | ALDH1A1MAPTATMLMNASMN1; SMN2 | |
| SCHEMBL28113541 | 0.64 | LMNA (0.41) | ALDH1A1MAPTATMLMNASMN1; SMN2 | |
| SCHEMBL22057583 | 0.64 | MAPT (0.47) | ALDH1A1MAPTATMLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |