Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18833346 | 0.90 | MTNR1A (0.41) | MTNR1AMTNR1BKDM4EKDM1AALDH1A1 | |
| SCHEMBL18833347 | 0.90 | MTNR1A (0.41) | MTNR1AMTNR1BKDM4EKDM1AALDH1A1 | |
| SCHEMBL5878664 | 0.90 | MTNR1A (0.40) | MTNR1AMTNR1BKDM4EKDM1AALDH1A1 | |
| SCHEMBL5877511 | 0.90 | MTNR1A (0.40) | MTNR1AMTNR1BKDM4EKDM1AALDH1A1 | |
| SCHEMBL5877507 | 0.90 | MTNR1A (0.40) | MTNR1AMTNR1BKDM4EKDM1AALDH1A1 | |
| SCHEMBL18867929 | 0.86 | TRPA1 (0.32) | KDM4EALDH1A1KMT2ATRPA1 | |
| SCHEMBL496006 | 0.84 | NFE2L2 (0.35) | KDM4ENFE2L2KMT2ATRPA1 | |
| SCHEMBL496007 | 0.84 | NFE2L2 (0.35) | KDM4ENFE2L2KMT2ATRPA1 | |
| SCHEMBL20415857 | 0.83 | CYP1A1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL17118206 | 0.83 | KDM4E (0.36) | KDM4EALDH1A1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10287220-B2 | Fluorination method | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2019-05-14 | — | — | US | disclosed |
| US-20170137341-A1 | FLUORINATION METHOD | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-05-18 | — | — | US | disclosed |
| WO-2015140572-A1 | FLUORINATION METHOD | ISIS INNOVATION LIMITED (GB) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10287220-B2 | Fluorination method | F13B, PPARG, PGC | MTNR1A 2789/4885MTNR1B 1635/4885KDM4E 1511/4885 |
| US-20170137341-A1 | FLUORINATION METHOD | F13B, PPARG, PGC | MTNR1A 2939/4885MTNR1B 1711/4885KDM4E 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.