Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5877511 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BALDH1A1MAPTKDM4E | |
| SCHEMBL5877507 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BALDH1A1MAPTKDM4E | |
| SCHEMBL17118232 | 0.90 | MTNR1A (0.41) | MTNR1AMTNR1BALDH1A1KDM4ECYP3A4 | |
| SCHEMBL18867930 | 0.87 | MAPT (0.36) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL18833347 | 0.85 | MTNR1A (0.41) | MTNR1AMTNR1BALDH1A1KDM4ELMNA | |
| SCHEMBL18833346 | 0.85 | MTNR1A (0.41) | MTNR1AMTNR1BALDH1A1KDM4ELMNA | |
| SCHEMBL18867929 | 0.79 | TRPA1 (0.32) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL18867932 | 0.74 | MEN1 (0.34) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL496007 | 0.74 | NFE2L2 (0.35) | MAPTKDM4EPOLBMEN1KMT2A | |
| SCHEMBL496006 | 0.74 | NFE2L2 (0.35) | MAPTKDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022872-B2 | Method for making fluorine labeled L-Dopa | MOLECULAR TECHNOLOGIES, INC. (US) | 2006-04-04 | — | — | US | claimed |
| US-20170137341-A1 | FLUORINATION METHOD | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137341-A1 | FLUORINATION METHOD | F13B, PPARG, PGC | MTNR1A 2939/4885MTNR1B 1711/4885ALDH1A1 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.