SCHEMBL1712191

SCHEMBL1712191

CCS(=O)(=O)Oc1cccc(OC)c1F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 1/20 0.40
KDM4E B2RXH2 2/20 0.40
CA1 P00915 4/20 0.37
CA2 P00918 4/20 0.37
CA12 O43570 3/20 0.37
CA14 Q9ULX7 3/20 0.37
CA7 P43166 2/20 0.37
CA9 Q16790 2/20 0.37
CA4 P22748 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
HTR6 P50406 1/20 0.36
ACHE P22303 1/20 0.36
NFE2L2 Q16236 1/20 0.36
ALPL P05186 1/20 0.35
ALPI P09923 1/20 0.35
ERN1 O75460 1/20 0.35
MRGPRX4 Q96LA9 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 2/20 0.35
ADRA2B P18089 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4132490 0.84 SLC6A2 (0.39) ALPLALPIL3MBTL1
SCHEMBL9958165 0.81 KAT6A (0.41) KAT6AKDM4ECA1CA2CA12
SCHEMBL14862234 0.81 CA12 (0.54) KDM4ECA1CA2CA12CA14
SCHEMBL630768 0.78 CA1 (0.58) KDM4ECA1CA2CA12CA14
SCHEMBL4130852 0.76 L3MBTL1 (0.46) KDM4ESMN1; SMN2TDP1ALDH1A1L3MBTL1
SCHEMBL1088018 0.75 ALPL (0.46) CA1CA2CA12CA14CA9
SCHEMBL172225 0.73 HTR2A (0.46) KDM4ECA1CA2CA12CA14
SCHEMBL1712187 0.72 HTR2A (0.40) KAT6AKDM4ECA1CA2CA12
SCHEMBL11715549 0.72 ALDH1A1 (0.53) KDM4ECA1CA2CA12CA14
SCHEMBL27871638 0.71 L3MBTL1 (0.42) KDM4ESMN1; SMN2ALPLALPITDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
EP-2200988-A1 N-BENZYL QUINOLINE-6-CARBOXAMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-06-30 EP disclosed
WO-2009157527-A1 BENZOTHIAZOLE CARBOXAMIDES AS FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-12-30 WO disclosed
WO-2009157528-A1 BENZOTHIAZOLE CARBOXAMIDES AS FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-12-30 WO disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed
WO-2009051086-A1 N-BENZYL QUINOLINE-6-CARBOXAMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 KAT6A 4280/4885KDM4E 3733/4885CA1 428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.