Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 8/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17123136 | 0.91 | ALDH1A1 (0.44) | HPGDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27312181 | 0.89 | MEN1 (0.45) | HPGDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27312182 | 0.89 | MEN1 (0.45) | HPGDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27312098 | 0.89 | MEN1 (0.45) | HPGDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL25128191 | 0.89 | MEN1 (0.45) | HPGDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL26375472 | 0.86 | MEN1 (0.47) | HPGDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13616087 | 0.85 | MEN1 (0.53) | HPGDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL24700121 | 0.85 | HPGD (0.45) | HPGDALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL26700919 | 0.84 | HPGD (0.45) | HPGDLMNAPKMTSHRCNR1 | |
| SCHEMBL26700881 | 0.84 | HPGD (0.45) | HPGDLMNAPKMTSHRCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158169-A1 | LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE | AUDAX PRIVATE DEBT LLC, AS AGENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158169-A1 | LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE | CTSA, CTSS, CTSV | HPGD 4459/4885ALDH1A1 3509/4885MEN1 3517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.