Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428967 | 0.84 | NOTUM (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL16912034 | 0.80 | AVPR2 (0.40) | KDM5AKDM4CKDM5BAVPR2ALDH1A1 | |
| SCHEMBL16910970 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL14130157 | 0.75 | MYC (0.61) | KDM5AKDM4CKDM5BAVPR2ALDH1A1 | |
| SCHEMBL14130164 | 0.75 | AVPR2 (0.48) | KDM5AKDM4CKDM5BAVPR2ALDH1A1 | |
| SCHEMBL19453172 | 0.74 | OXTR (0.48) | ALDH1A1MAPTATMSMN1; SMN2POLB | |
| SCHEMBL29400917 | 0.73 | ALDH1A1 (0.47) | KDM5AKDM4CKDM5BALDH1A1MAPT | |
| SCHEMBL21023834 | 0.72 | RXRA (0.50) | ALDH1A1MAPTATMSMN1; SMN2NPC1 | |
| SCHEMBL6620361 | 0.72 | AVPR2 (0.46) | KDM5AKDM4CKDM5BAVPR2ALDH1A1 | |
| SCHEMBL16505171 | 0.72 | PDE10A (0.39) | KDM5AKDM4CKDM5BAVPR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9826741-B2 | Tetrazolinone compound and application thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-28 | — | — | US | disclosed |
| US-20170105415-A1 | TETRAZOLINONE COMPOUND AND APPLICATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170105415-A1 | TETRAZOLINONE COMPOUND AND APPLICATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| WO-2015147332-A1 | TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME | 住友化学株式会社 | 2015-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105415-A1 | TETRAZOLINONE COMPOUND AND APPLICATION THEREOF | KCNK4, CASP4, KCNA4 | KDM5A 2679/4885KDM4C 787/4885KDM5B 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.