Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 6/20 | 0.46 |
| ▸ | RORC | P51449 | 6/20 | 0.46 |
| ▸ | RORB | Q92753 | 6/20 | 0.46 |
| ▸ | GHSR | Q92847 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18407425 | 0.83 | GPR84 (0.47) | RORARORCRORBGHSRGPR84 | |
| SCHEMBL28784738 | 0.80 | CTSV (0.52) | RORARORCRORBGPR84PGR | |
| SCHEMBL31619137 | 0.80 | CTSV (0.52) | RORARORCRORBGPR84PGR | |
| Schinifoline SCHEMBL27713119 | 0.80 | CTSV (0.52) | RORARORCRORBGPR84PGR | |
| SCHEMBL5463807 | 0.80 | CTSV (0.52) | RORARORCRORBGPR84PGR | |
| SCHEMBL7913379 | 0.78 | CTSV (0.50) | RORARORCRORBGPR84PGR | |
| SCHEMBL18415626 | 0.75 | KIF11 (0.47) | RORARORCRORBPGRCYP2C9 | |
| SCHEMBL17145105 | 0.74 | GHSR (0.79) | GHSRGPR84KIF11CTSVCTSL | |
| SCHEMBL12278995 | 0.74 | GPR84 (0.47) | RORARORCRORBGPR84 | |
| SCHEMBL12279243 | 0.74 | GPR84 (0.47) | RORARORCRORBGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10472326-B2 | PQSR modulators | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-11-12 | — | — | US | disclosed |
| US-10472326-B2 | PQSR modulators | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-11-12 | — | — | US | disclosed |
| EP-3126333-B1 | PQSR MODULATORS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2018-08-01 | — | — | EP | disclosed |
| EP-3126333-A1 | PQSR MODULATORS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2017-02-08 | — | — | EP | disclosed |
| US-20170022165-A1 | PQSR MODULATORS | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2017-01-26 | — | — | US | disclosed |
| US-20170022165-A1 | PQSR MODULATORS | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2017-01-26 | — | — | US | disclosed |
| WO-2015149821-A1 | PQSR MODULATORS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2015-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10472326-B2 | PQSR modulators | QARS1, SRPRA, MRPS35 | RORA 351/4885RORC 333/4885RORB 281/4885 |
| US-20170022165-A1 | PQSR MODULATORS | QARS1, SRPRA, MRPS35 | RORA 351/4885RORC 333/4885RORB 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.