Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.47 |
| ▸ | RORA | P35398 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | RORB | Q92753 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28784738 | 0.83 | CTSV (0.52) | GPR84RORARORCRORBPGR | |
| Schinifoline SCHEMBL27713119 | 0.83 | CTSV (0.52) | GPR84RORARORCRORBPGR | |
| SCHEMBL31619137 | 0.83 | CTSV (0.52) | GPR84RORARORCRORBPGR | |
| SCHEMBL5463807 | 0.83 | CTSV (0.52) | GPR84RORARORCRORBPGR | |
| SCHEMBL17144929 | 0.83 | RORA (0.46) | GPR84RORARORCRORBPGR | |
| SCHEMBL7913379 | 0.81 | CTSV (0.50) | GPR84RORARORCRORBPGR | |
| SCHEMBL30282852 | 0.78 | TLR8 (0.44) | GPR84RORARORCRORBPGR | |
| SCHEMBL12279243 | 0.77 | GPR84 (0.47) | GPR84RORARORCRORBOXER1 | |
| SCHEMBL12278376 | 0.77 | GPR84 (0.47) | GPR84RORARORCRORBOXER1 | |
| SCHEMBL12278342 | 0.77 | GPR84 (0.47) | GPR84RORARORCRORBOXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022165-A1 | PQSR MODULATORS | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022165-A1 | PQSR MODULATORS | QARS1, SRPRA, MRPS35 | GPR84 501/4885RORA 351/4885RORC 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.