Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.44 |
| ▸ | GLRB | P48167 | 1/20 | 0.44 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24934252 | 0.83 | CDK8 (0.49) | GLRA3GLRBIL2HPGDSALDH1A1 | |
| SCHEMBL30999881 | 0.80 | ALDH1A1 (0.47) | GLRA3GLRBIL2HPGDSALDH1A1 | |
| SCHEMBL24933996 | 0.80 | ALDH1A1 (0.47) | GLRA3GLRBIL2HPGDSALDH1A1 | |
| SCHEMBL9507238 | 0.78 | BRD4 (0.48) | GLRA3GLRBHPGDSMAPK1BRD4 | |
| SCHEMBL31216543 | 0.78 | KAT6A (0.44) | GLRA3GLRBHPGDSALDH1A1HPGD | |
| SCHEMBL6434655 | 0.78 | GLRA3 (0.62) | GLRA3GLRBHPGDSNPC1RAB9A | |
| SCHEMBL939928 | 0.77 | KEAP1 (0.55) | GLRA3GLRBHPGDSALDH1A1NPC1 | |
| SCHEMBL31558442 | 0.77 | KEAP1 (0.55) | GLRA3GLRBHPGDSALDH1A1NPC1 | |
| SCHEMBL6433748 | 0.76 | HPGDS (0.47) | GLRA3GLRBIL2HPGDSALDH1A1 | |
| SCHEMBL6573037 | 0.76 | PRKCI (0.50) | GLRA3GLRBHPGDSNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046916-B1 | OXAZOLE TRIPLET EMITTERS FOR OLED APPLICATIONS | MERCK PATENT GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |