Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | BRD2 | P25440 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | CDK8 | P49336 | 2/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.47 |
| ▸ | MST1R | Q04912 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939928 | 0.86 | KEAP1 (0.55) | HPGDSGLRA3GLRB | |
| SCHEMBL31558442 | 0.86 | KEAP1 (0.55) | HPGDSGLRA3GLRB | |
| SCHEMBL6433748 | 0.84 | HPGDS (0.47) | BRD4HPGDSGLRA3GLRBJAK3 | |
| SCHEMBL6573037 | 0.84 | PRKCI (0.50) | HPGDSCDK8GSK3BGLRA3GLRB | |
| SCHEMBL24934252 | 0.84 | CDK8 (0.49) | HPGDSMAP4K4CDK8LRRK2FGFR1 | |
| SCHEMBL6434655 | 0.84 | GLRA3 (0.62) | HPGDSCDK8ROCK1ABL1GLRA3 | |
| SCHEMBL30999881 | 0.81 | ALDH1A1 (0.47) | HPGDSGLRA3GLRBLMNAMAPK1 | |
| SCHEMBL24933996 | 0.81 | ALDH1A1 (0.47) | HPGDSGLRA3GLRBLMNAMAPK1 | |
| SCHEMBL6514687 | 0.80 | BRD4 (0.49) | BRD4HPGDSMAP4K4CLK4KDR | |
| SCHEMBL6438972 | 0.80 | HPGDS (0.47) | HPGDSGLRA3GLRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000477-B2 | Dopamine D3 receptor antagonist compounds | INDIVIOR UK LIMITED (GB) | 2018-06-19 | — | — | US | disclosed |
| US-20170334895-A1 | DOPAMINE D3 RECEPTOR ANTAGONIST COMPOUNDS | INDIVIOR INC. | 2017-11-23 | — | — | US | disclosed |
| EP-0297804-B1 | SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-4863846-A | SULFUR | KONICA CORPORATION (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0297804-A2 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1989-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000477-B2 | Dopamine D3 receptor antagonist compounds | DRD3, DRD2, DRD4 | BRD4 1241/4885BRD2 1185/4885CREBBP 2063/4885 |
| US-20170334895-A1 | DOPAMINE D3 RECEPTOR ANTAGONIST COMPOUNDS | DRD3, DRD2, DRD4 | BRD4 1241/4885BRD2 1185/4885CREBBP 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.