Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148071 | 0.91 | HTR6 (0.42) | HTR6KDM4EHTR2ALMNATP53 | |
| SCHEMBL6673091 | 0.81 | HTR6 (0.53) | HTR6KDM4EHTR2ALMNATP53 | |
| SCHEMBL1949777 | 0.81 | HTR6 (0.53) | HTR6KDM4EHTR2ALMNATP53 | |
| SCHEMBL6675770 | 0.79 | HTR6 (0.51) | HTR6KDM4EHTR2ALMNATP53 | |
| SCHEMBL6675371 | 0.79 | HTR6 (0.51) | HTR6KDM4EHTR2ALMNATP53 | |
| SCHEMBL1028711 | 0.78 | HTR6 (0.47) | HTR6KDM4EHTR2ALMNATP53 | |
| SCHEMBL668105 | 0.77 | HTR6 (0.56) | HTR6KDM4EHTR2ALMNATP53 | |
| SCHEMBL6066970 | 0.77 | HTR6 (0.41) | HTR6KDM4EHTR2ALMNATP53 | |
| SCHEMBL2641527 | 0.77 | HTR6 (0.46) | HTR6KDM4EHTR2ALMNATP53 | |
| SCHEMBL29546963 | 0.77 | HTR6 (0.46) | HTR6KDM4EHTR2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701771-B2 | Substituted zirconocenes catalysts and methods of use in polymerization reactions | BASELL POLYOLEFINE GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-9701771-B2 | Substituted zirconocenes catalysts and methods of use in polymerization reactions | BASELL POLYOLEFINE GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-9422380-B2 | Non-bridged metallocene complexes for the polymerization of olefins | Basell Polyolefine Wesseling (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9422380-B2 | Non-bridged metallocene complexes for the polymerization of olefins | Basell Polyolefine Wesseling (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9422319-B2 | Bisaryl metallocenes and use thereof to produce polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9422319-B2 | Bisaryl metallocenes and use thereof to produce polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284489-A1 | NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284490-A1 | SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284490-A1 | SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284489-A1 | NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | PCBP1, PARG, PARN | HTR6 4180/4885KDM4E 3356/4885HTR2A 2670/4885 |
| US-20150284490-A1 | SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS | MAOA, MPO, PARP1 | HTR6 1624/4885KDM4E 1471/4885HTR2A 586/4885 |
| US-20150284489-A1 | NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS | PCBP1, MORF4L1, PPIL4 | HTR6 4185/4885KDM4E 2960/4885HTR2A 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.