SCHEMBL17147180

SCHEMBL17147180

COc1c(C)cc(C2=CCC(C)=C2)cc1C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10030804 0.72 ACHE (0.43) ALDH1A1
SCHEMBL8400954 0.66 ALDH1A1 (0.42) ALDH1A1
SCHEMBL1824459 0.66 ALDH1A1 (0.35) ALDH1A1
SCHEMBL7635776 0.66 ALDH1A1 (0.35) ALDH1A1
SCHEMBL20597865 0.64
SCHEMBL19596581 0.63 CA1 (0.67) ALDH1A1
SCHEMBL6966078 0.63 CNR1 (0.35) ALDH1A1
SCHEMBL17135804 0.63 ACHE (0.37)
SCHEMBL17147179 0.63 CYP1A2 (0.34) ALDH1A1
SCHEMBL3686784 0.63 ACHE (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9701771-B2 Substituted zirconocenes catalysts and methods of use in polymerization reactions BASELL POLYOLEFINE GMBH (DE) 2017-07-11 US disclosed
US-9701771-B2 Substituted zirconocenes catalysts and methods of use in polymerization reactions BASELL POLYOLEFINE GMBH (DE) 2017-07-11 US disclosed
US-9422380-B2 Non-bridged metallocene complexes for the polymerization of olefins Basell Polyolefine Wesseling (DE) 2016-08-23 US disclosed
US-9422380-B2 Non-bridged metallocene complexes for the polymerization of olefins Basell Polyolefine Wesseling (DE) 2016-08-23 US disclosed
US-9422319-B2 Bisaryl metallocenes and use thereof to produce polyolefins BASELL POLYOLEFINE GMBH (DE) 2016-08-23 US disclosed
US-9422319-B2 Bisaryl metallocenes and use thereof to produce polyolefins BASELL POLYOLEFINE GMBH (DE) 2016-08-23 US disclosed
US-20150284418-A1 BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS BASELL POLYOLEFIN GMBH (DE) 2015-10-08 US disclosed
US-20150284489-A1 NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2015-10-08 US disclosed
US-20150284489-A1 NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2015-10-08 US disclosed
US-20150284490-A1 SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS BASELL POLYOLEFIN GMBH (DE) 2015-10-08 US disclosed
US-20150284490-A1 SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS BASELL POLYOLEFIN GMBH (DE) 2015-10-08 US disclosed
US-20150284418-A1 BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS BASELL POLYOLEFIN GMBH (DE) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284418-A1 BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS PCBP1, PARG, PARN ALDH1A1 1970/4885
US-20150284490-A1 SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS MAOA, MPO, PARP1 ALDH1A1 1440/4885
US-20150284489-A1 NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS PCBP1, MORF4L1, PPIL4 ALDH1A1 2151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.