Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12559141 | 0.89 | AKR1C3 (0.35) | AKR1C3MTNR1AMTNR1BHPGDMEP1B | |
| SCHEMBL1163084 | 0.79 | MEN1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL1163394 | 0.79 | AKR1C3 (0.36) | AKR1C3GAAALDH1A1HPGD | |
| SCHEMBL12595704 | 0.78 | MTNR1A (0.32) | MTNR1AMTNR1BKDM4EMEP1B | |
| SCHEMBL12559042 | 0.74 | MTNR1A (0.39) | AKR1C3MTNR1AMTNR1BHPGD | |
| SCHEMBL31063501 | 0.67 | HSD17B10 (0.38) | MTNR1AMTNR1BTUBB1HSP90AB1KDM4E | |
| SCHEMBL30822592 | 0.67 | HSP90AB1 (0.38) | AKR1C3MTNR1AMTNR1BTUBB1HSP90AB1 | |
| SCHEMBL2126802 | 0.67 | HSP90AB1 (0.56) | TUBB1HSP90AB1GAAALDH1A1ACACB | |
| SCHEMBL1163373 | 0.67 | HSD17B10 (0.35) | AKR1C3HSP90AB1GAAALDH1A1HPGD | |
| SCHEMBL12559178 | 0.67 | THRB (0.39) | AKR1C3GAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284365-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION (US) | 2015-10-08 | — | — | US | disclosed |
| US-20150284365-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION (US) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284365-A1 | COMPOUNDS AND METHODS OF USE THEREOF | AANAT, HNMT, INMT | AKR1C3 1365/4885MTNR1A 65/4885MTNR1B 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.