Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19692614 | 0.81 | MARS1 (0.39) | RNPEPHTTCYP3A4CYP2C19METAP2 | |
| SCHEMBL19692615 | 0.81 | MARS1 (0.39) | RNPEPHTTCYP3A4CYP2C19METAP2 | |
| SCHEMBL10197497 | 0.79 | GABRR1 (0.45) | — | |
| SCHEMBL9973365 | 0.76 | SMN1; SMN2 (0.40) | HTTGAAL3MBTL1 | |
| SCHEMBL15041051 | 0.74 | CYP2C9 (0.44) | RNPEPHTTCYP3A4CYP2C19METAP2 | |
| SCHEMBL5546583 | 0.74 | CYP2C9 (0.44) | RNPEPHTTCYP3A4CYP2C19METAP2 | |
| SCHEMBL13103971 | 0.74 | CYP2C9 (0.44) | RNPEPHTTCYP3A4CYP2C19METAP2 | |
| SCHEMBL8541750 | 0.72 | KISS1R (0.35) | HTT | |
| SCHEMBL14816860 | 0.72 | METAP2 (0.50) | RNPEPCYP3A4CYP2C19METAP2METAP1 | |
| SCHEMBL15907912 | 0.71 | PKM (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150283227-A1 | SYNTHETIC ENV PROTEINS | DANA-FARBER CANCER INSTITUTE | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283227-A1 | SYNTHETIC ENV PROTEINS | CD4, EEA1, FURIN | RNPEP 147/4885HTT 2078/4885CYP3A4 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.