SCHEMBL25667145

SCHEMBL25667145

COCCOc1c(C)cc2ccccc2c1-c1c(OCCOC(C)=O)ccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KMT2A Q03164 2/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 3/20 0.38
PTGS2 P35354 3/20 0.38
MMP3 P08254 1/20 0.37
MEN1 O00255 1/20 0.36
ALOX5 P09917 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTT P42858 1/20 0.36
KDM1A O60341 1/20 0.35
RAD52 P43351 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17148019 0.89 MAPT (0.47) KDM4EALDH1A1HPGDL3MBTL1MAPT
SCHEMBL25913703 0.77 MAPT (0.45) KDM4EALDH1A1HPGDL3MBTL1MAPT
SCHEMBL22416800 0.74 MAPT (0.53) KDM4EALDH1A1KMT2AL3MBTL1MAPT
SCHEMBL17148017 0.73 MAPT (0.49) HPGDKMT2AMAPTPTGS2MEN1
SCHEMBL26935165 0.73 MMP3 (0.39) KDM4EALDH1A1HPGDMAPTPTGS2
SCHEMBL10398142 0.72 MAPT (0.44) KDM4EALDH1A1HPGDL3MBTL1MAPT
SCHEMBL29506862 0.71 ALDH1A1 (0.41) KDM4EALDH1A1HPGDNPSR1KMT2A
SCHEMBL1902160 0.71 KDM4E (0.64) KDM4EALDH1A1HPGD
SCHEMBL21462995 0.71 ALDH1A1 (0.41) KDM4EALDH1A1HPGDNPSR1KMT2A
SCHEMBL13210145 0.70 NCEH1 (0.56) KDM4EALDH1A1HPGDL3MBTL1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192950-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER TEIJIN LIMITED (JP) 2023-06-22 US disclosed