SCHEMBL17150243

SCHEMBL17150243

c1ccc([Si](c2ccccc2)(c2ccccc2)c2cccc(-n3c4ccccc4n4c5ccccc5nc34)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
ADORA1 P30542 4/20 0.35
ADORA2B P29275 1/20 0.35
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 4/20 0.34
MAPT P10636 3/20 0.34
HPGD P15428 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TSHR P16473 2/20 0.34
ADORA3 P0DMS8 3/20 0.34
ADORA2A P29274 3/20 0.34
LCK P06239 2/20 0.33
SRC P12931 2/20 0.33
LMNA P02545 2/20 0.33
TP53 P04637 2/20 0.33
HSD17B10 Q99714 2/20 0.33
POLB P06746 1/20 0.33
CRHBP P24387 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18701288 1.00 MAPK1 (0.39) MAPK1HTTADORA1ADORA2BKDM4E
SCHEMBL17150262 0.99 MAPK1 (0.38) MAPK1HTTADORA1ADORA2BKDM4E
SCHEMBL17150268 0.99 MAPK1 (0.38) MAPK1HTTADORA1ADORA2BKDM4E
SCHEMBL17150259 0.99 MAPK1 (0.38) MAPK1HTTADORA1ADORA2BKDM4E
SCHEMBL18701346 0.95 MAPK1 (0.35) MAPK1HTTADORA1ADORA2BKDM4E
SCHEMBL18701354 0.95 MAPK1 (0.35) MAPK1HTTADORA1ADORA2BKDM4E
SCHEMBL18407031 0.94 MAPK1 (0.38) MAPK1HTTADORA1ADORA2BKDM4E
SCHEMBL17150239 0.93 MAPK1 (0.36) MAPK1HTTADORA1ADORA2BKDM4E
SCHEMBL23622780 0.93 MAPK1 (0.34) MAPK1HTTADORA1ADORA2BKDM4E
SCHEMBL18407030 0.93 MAPK1 (0.37) MAPK1HTTADORA1ADORA2BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329089-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
US-20230329089-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
US-20230287017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230292593-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230292593-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230279029-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 US disclosed
US-20230192729-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230192729-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20200220085-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2020-07-09 US disclosed
US-20200203636-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-25 US disclosed
EP-3126368-B1 SILYL-BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE AS HOST FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2020-04-29 EP disclosed
US-20170098783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2017-04-06 US disclosed
US-20170098783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2017-04-06 US disclosed
US-20170025627-A1 SILYL-BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE AS HOST FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2017-01-26 US disclosed
US-20170025627-A1 SILYL-BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE AS HOST FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2017-01-26 US disclosed
WO-2015150234-A1 SILYL-BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE AS HOST FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2015-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170098783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EED, EML4, MT-ND4L MAPK1 1973/4885HTT 122/4885ADORA1 2124/4885
US-20230287017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, NONO MAPK1 3249/4885HTT 2640/4885ADORA1 3000/4885
US-20200220085-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EED, EML4, MT-ND4L MAPK1 1973/4885HTT 122/4885ADORA1 2124/4885
US-20230329089-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR1H2, OXER1, NR1H3 MAPK1 830/4885HTT 3729/4885ADORA1 1766/4885
US-20170025627-A1 SILYL-BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE AS HOST FOR ORGANIC LIGHT EMITTING DIODES CCNI, SLCO4C1, SLCO2A1 MAPK1 950/4885HTT 2364/4885ADORA1 2866/4885
US-20230192729-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE LAGE3, EMC1, CYP2E1 MAPK1 306/4885HTT 2756/4885ADORA1 1707/4885
US-20230279029-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, EHD1 MAPK1 3284/4885HTT 222/4885ADORA1 4660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.