SCHEMBL17152091

SCHEMBL17152091

CC1(C)c2ccccc2-c2cc(-c3ccc4ccccc4c3-c3nc(-c4ccc5ccc6ccccc6c5c4)nc(-c4ccc5ccc6ccccc6c5c4)n3)ccc21

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HIF1A Q16665 1/20 0.31
CYP1B1 Q16678 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17151647 0.94 SOS1 (0.33) DNMT1ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL17151987 0.94 DNMT1 (0.32) DNMT1ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL17151842 0.93 HDAC4 (0.35) DNMT1
SCHEMBL17151837 0.91 MAPT (0.34) DNMT1ALDH1A1HSD17B10
SCHEMBL17152095 0.91 ALDH1A1 (0.33) ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL17152039 0.90 PDK2 (0.33) ALDH1A1HSD17B10
SCHEMBL18386082 0.90 GPR84 (0.32) DNMT1ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL17151866 0.89 S1PR1 (0.35) DNMT1ALDH1A1HSD17B10
SCHEMBL17151637 0.88 SOS1 (0.33) DNMT1ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL17152098 0.88 S1PR1 (0.34) ALDH1A1HIF1ACYP1B1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 US disclosed
US-10381572-B2 Heterocyclic compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2019-08-13 US disclosed
US-20170018718-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-01-19 US disclosed
US-20170018718-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-01-19 US disclosed
WO-2015152651-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2015-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10381572-B2 Heterocyclic compound and organic light-emitting element comprising same CRY1, CRY2, PER2 DNMT1 836/4885ALDH1A1 1107/4885HIF1A 2139/4885
US-20170018718-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 DNMT1 836/4885ALDH1A1 1107/4885HIF1A 2139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.