Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648225 | 0.83 | CYP2A6 (0.43) | KCNA3GAAKDM4EALDH1A1HPGD | |
| SCHEMBL11064554 | 0.80 | KCNA3 (0.40) | KCNA3GAAKDM4EALDH1A1HPGD | |
| SCHEMBL10776993 | 0.80 | CDK2 (0.43) | KCNA3GAAKDM4EALDH1A1HPGD | |
| SCHEMBL7399139 | 0.80 | DDB1 (0.46) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17154500 | 0.79 | HTR7 (0.51) | KDM4EALDH1A1 | |
| SCHEMBL4593117 | 0.79 | PRKCA (0.45) | KCNA3GAAKDM4EALDH1A1HPGD | |
| SCHEMBL9596671 | 0.79 | KCNA3 (0.42) | KCNA3GAAKDM4EALDH1A1HPGD | |
| Water SCHEMBL8678456 | 0.78 | DDB1 (0.45) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2701829 | 0.76 | GSK3B (0.42) | KCNA3GAAKDM4EALDH1A1HPGD | |
| SCHEMBL10895518 | 0.75 | GAA (0.39) | KCNA3GAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015153410-A1 | HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-10-08 | — | — | WO | disclosed |