Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.39 |
| ▸ | HPGD | P15428 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | GLA | P06280 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.39 |
| ▸ | CASP1 | P29466 | 6/20 | 0.39 |
| ▸ | CASP7 | P55210 | 6/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17158332 | 1.00 | KDM4E (0.39) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL26128039 | 0.73 | CA12 (0.48) | KDM4EALDH1A1HSD17B10ATMCA12 | |
| SCHEMBL7714514 | 0.72 | MEN1 (0.38) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL17158191 | 0.72 | CA12 (0.47) | KDM4EATMCA12CA9TSHR | |
| SCHEMBL16684902 | 0.71 | ALOX5 (0.43) | KDM4EHPGDALDH1A1HSD17B10ATM | |
| SCHEMBL21585542 | 0.66 | ALDH1A1 (0.47) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL22541045 | 0.66 | TSHR (0.42) | KDM4EHPGDALDH1A1GAAHSD17B10 | |
| SCHEMBL8306654 | 0.65 | RAB9A (0.38) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL3570507 | 0.65 | CHRNB2 (0.47) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL31422915 | 0.63 | PARP10 (0.33) | KDM4EGAAMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940008-B1 | NOVEL BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | SANWA KAGAKU KENKYUSHO CO (JP) | 2017-05-17 | — | — | EP | disclosed |
| US-9586905-B2 | Benzoazepine derivative and medical use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2017-03-07 | — | — | US | disclosed |
| EP-2940008-A1 | NOVEL BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-20150291533-A1 | NOVEL BENZOAZEPINE DERIVATIVE AND MEDICAL USE THEREOF | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291533-A1 | NOVEL BENZOAZEPINE DERIVATIVE AND MEDICAL USE THEREOF | AVPR2, AVPR1A, AVPR1B | KDM4E 1386/4885HPGD 1550/4885ALDH1A1 1975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.