Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 9/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17159739 | 0.82 | TBXAS1 (0.42) | CYP2A6CYP11B2GAAMAPTCYP2E1 | |
| SCHEMBL30522569 | 0.79 | CYP11B2 (0.53) | CYP2A6CYP11B2MAPTCYP2E1CYP2C9 | |
| SCHEMBL17159707 | 0.74 | KDM4E (0.41) | MAPTCYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL16200083 | 0.73 | ALDH1A1 (0.48) | CYP2A6CYP11B2CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL30522602 | 0.69 | CYP11B2 (0.49) | CYP2A6CYP11B2MAPTCYP2E1CYP2C9 | |
| SCHEMBL17159750 | 0.69 | PDE10A (0.39) | CYP2A6MAPT | |
| SCHEMBL18818721 | 0.68 | CYP2A6 (0.67) | CYP2A6MAPTCYP2E1CYP2C9CYP2B6 | |
| SCHEMBL30230959 | 0.67 | CYP11B2 (0.50) | CYP2A6CYP11B2MAPTCYP2E1CYP2C9 | |
| SCHEMBL19453173 | 0.66 | CYP2A6 (0.50) | CYP2A6CYP11B2MAPTCYP2E1CYP2C9 | |
| SCHEMBL30522561 | 0.66 | CYP2A6 (0.47) | CYP2A6CYP11B2GAAMAPTCYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944634-B2 | Pyrazolopyridine derivatives as TTX-S blockers | RAQUALIA PHARMA INC. (JP) | 2018-04-17 | — | — | US | disclosed |
| US-20150291582-A1 | PYRAZOLOPYRIDINE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291582-A1 | PYRAZOLOPYRIDINE DERIVATIVES AS TTX-S BLOCKERS | SCN5A, KCNH2, CACNA1G | CYP2A6 3804/4885CYP11B2 3121/4885GAA 1539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.