Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL1573659 | 0.81 | LMNA (0.65) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL10611921 | 0.81 | LMNA (0.65) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL4458162 | 0.81 | LMNA (0.65) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL10900065 | 0.81 | LMNA (0.65) | LMNAACHETSHRALOX12POLB | |
| Aniline SCHEMBL28208327 | 0.81 | ADRA2C (0.48) | LMNAACHETSHRPOLBSIGMAR1 | |
| Toluene SCHEMBL1459338 | 0.79 | LMNA (0.55) | LMNAACHETSHRALOX12POLB | |
| SCHEMBL20815494 | 0.79 | LMNA (0.45) | LMNAACHETSHRPOLBSIGMAR1 | |
| SCHEMBL1207697 | 0.79 | LMNA (0.45) | LMNAACHETSHRPOLBSIGMAR1 | |
| Toluene SCHEMBL11479355 | 0.79 | LMNA (0.61) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL11325304 | 0.78 | LMNA (0.69) | LMNAACHETSHRALOX12POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015155713-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF 1,3, 4 -SUBSTITUTED PYRAZOLES | ISAGRO S.P.A. (IT) | 2015-10-15 | — | — | WO | disclosed |