Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114799 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL16437865 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10050599 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL138329 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10301493 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14883433 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL16926031 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL8285384 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20683157 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL102247 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005791-B2 | O-demethylating process of methoxy substituted morphinan-6-one derivatives | NORAMCO GMBH (CH) | 2018-06-26 | — | — | US | disclosed |
| US-10005791-B2 | O-demethylating process of methoxy substituted morphinan-6-one derivatives | NORAMCO GMBH (CH) | 2018-06-26 | — | — | US | disclosed |
| EP-3129383-B1 | O-DEMETHYLATING PROCESS OF METHOXY SUBSTITUTED MORPHINAN-6-ONE DERIVATIVES | CILAG AG (CH) | 2018-02-28 | — | — | EP | disclosed |
| EP-2580201-B1 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF | RHODES TECH (US) | 2017-08-02 | — | — | EP | disclosed |
| US-20170022211-A1 | O-DEMETHYLATING PROCESS OF METHOXY SUBSTITUTED MORPHINAN-6-ONE DERIVATIVES | CILAG AG (CH) | 2017-01-26 | — | — | US | disclosed |
| US-20170022211-A1 | O-DEMETHYLATING PROCESS OF METHOXY SUBSTITUTED MORPHINAN-6-ONE DERIVATIVES | CILAG AG (CH) | 2017-01-26 | — | — | US | disclosed |
| WO-2015155181-A1 | O-DEMETHYLATING PROCESS OF METHOXY SUBSTITUTED MORPHINAN-6-ONE DERIVATIVES | CILAG AG (CH) | 2015-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022211-A1 | O-DEMETHYLATING PROCESS OF METHOXY SUBSTITUTED MORPHINAN-6-ONE DERIVATIVES | TET2, ALKBH5, METTL3 | OPRM1 101/4885OPRD1 251/4885OPRK1 404/4885 |
| US-10005791-B2 | O-demethylating process of methoxy substituted morphinan-6-one derivatives | TET2, ALKBH5, METTL3 | OPRM1 111/4885OPRD1 277/4885OPRK1 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.