Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114799 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL17168337 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL16437865 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10050599 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL138329 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10301493 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14883433 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL16926031 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL8285384 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20683157 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200338068-A1 | PROCESSES FOR PREPARING MORPHINAN-6-ONE PRODUCTS WITH LOW LEVELS OF a,ß-UNSATURATED KETONE COMPOUNDS | SpecGx LLC (US) | 2020-10-29 | — | — | US | disclosed |
| US-20190225622-A1 | Process for the Preparation of Oxymorphone Alkaloid and Oxymorphone Salts | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-07-25 | — | — | US | disclosed |
| US-20180008596-A1 | Processes For Preparing Morphinan-6-One Products With Low Levels Of Alpha, Beta-Unsaturated Ketone Compounds | MALLINCKRODT LLC (US) | 2018-01-11 | — | — | US | disclosed |
| US-20150329553-A1 | Process for the preparation of oxymorphone alkaloid and oxymorphone salts | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2015-11-19 | — | — | US | disclosed |
| US-9120800-B2 | Process for the preparation of oxymorphone alkaloid and oxymorphone salts | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2015-09-01 | — | — | US | disclosed |
| US-20150148365-A1 | Processes For Preparing Morphinan-6-One Products With Low Levels Of Alpha, Beta-Unsaturated Ketone Compounds | LIEBEL-FLARSHEIM COMPANY LLC | 2015-05-28 | — | — | US | disclosed |
| WO-2015015146-A1 | PROCESS FOR THE PREPARATION OF OXYMORPHONE | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2015-02-05 | — | — | WO | disclosed |
| US-20150038715-A1 | PROCESS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2015-02-05 | — | — | US | disclosed |
| US-8871779-B2 | Process for preparing morphinan-6-one products with low levels of α,β-unsaturated ketone compounds | MALLINCKRODT LLC (US) | 2014-10-28 | — | — | US | disclosed |
| US-8871779-B2 | Process for preparing morphinan-6-one products with low levels of α,β-unsaturated ketone compounds | MALLINCKRODT LLC (US) | 2014-10-28 | — | — | US | disclosed |
| US-8748611-B2 | Processes for preparing morphinan-6-one products with low levels of alpha beta-unsaturated compounds | MALLINCKRODT LLC (US) | 2014-06-10 | — | — | US | disclosed |
| US-8748611-B2 | Processes for preparing morphinan-6-one products with low levels of alpha beta-unsaturated compounds | MALLINCKRODT LLC (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120059167-A1 | PROCESSES FOR PREPARING MORPHINAN-6-ONE PRODUCTS WITH LOW LEVELS OF ALPHA BETA-UNSATURATED COMPOUNDS | MALLINCKRODT INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120059167-A1 | PROCESSES FOR PREPARING MORPHINAN-6-ONE PRODUCTS WITH LOW LEVELS OF ALPHA BETA-UNSATURATED COMPOUNDS | MALLINCKRODT INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20080312442-A1 | Process for Preparing Morphinan-6-One Products with Low Levels of Alpha, Beta-Unsaturated Ketone Compounds | SpecGx LLC | 2008-12-18 | — | — | US | disclosed |
| US-20080312442-A1 | Process for Preparing Morphinan-6-One Products with Low Levels of Alpha, Beta-Unsaturated Ketone Compounds | SpecGx LLC | 2008-12-18 | — | — | US | disclosed |
| WO-2007103105-A2 | PROCESSES FOR PREPARING MORPHINAN-6-ONE PRODUCTS WITH LOW LEVELS OF ALPHA, BETA-UNSATURATED KETONE COMPOUNDS | MALLINCKRODT INC. (US) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225622-A1 | Process for the Preparation of Oxymorphone Alkaloid and Oxymorphone Salts | OPRK1, OPRM1, OPRD1 | OPRM1 2/4885OPRD1 3/4885OPRK1 1/4885 |
| US-20080312442-A1 | Process for Preparing Morphinan-6-One Products with Low Levels of Alpha, Beta-Unsaturated Ketone Compounds | FASN, CYP1B1, SULT1A1 | OPRM1 73/4885OPRD1 46/4885OPRK1 105/4885 |
| US-20150329553-A1 | Process for the preparation of oxymorphone alkaloid and oxymorphone salts | OPRK1, OPRM1, OPRD1 | OPRM1 2/4885OPRD1 3/4885OPRK1 1/4885 |
| US-20200338068-A1 | PROCESSES FOR PREPARING MORPHINAN-6-ONE PRODUCTS WITH LOW LEVELS OF a,ß-UNSATURATED KETONE COMPOUNDS | FASN, CYP1B1, CLN6 | OPRM1 76/4885OPRD1 62/4885OPRK1 123/4885 |
| US-20150148365-A1 | Processes For Preparing Morphinan-6-One Products With Low Levels Of Alpha, Beta-Unsaturated Ketone Compounds | FASN, CYP1B1, CLN6 | OPRM1 69/4885OPRD1 50/4885OPRK1 98/4885 |
| US-20120059167-A1 | PROCESSES FOR PREPARING MORPHINAN-6-ONE PRODUCTS WITH LOW LEVELS OF ALPHA BETA-UNSATURATED COMPOUNDS | FASN, DEGS1, CYP1B1 | OPRM1 87/4885OPRD1 61/4885OPRK1 163/4885 |
| US-20150038715-A1 | PROCESS | OPRK1, OPRD1, HMOX1 | OPRM1 4/4885OPRD1 2/4885OPRK1 1/4885 |
| US-20180008596-A1 | Processes For Preparing Morphinan-6-One Products With Low Levels Of Alpha, Beta-Unsaturated Ketone Compounds | FASN, CYP1B1, CLN6 | OPRM1 69/4885OPRD1 50/4885OPRK1 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.