Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147327 | 0.97 | LMNA (0.57) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| Bromide SCHEMBL11745160 | 0.93 | LMNA (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| Iodide SCHEMBL29644490 | 0.93 | LMNA (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL11777482 | 0.89 | TSHR (0.50) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| Fluoride SCHEMBL4074826 | 0.88 | LMNA (0.47) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| Fluoride SCHEMBL4074823 | 0.88 | LMNA (0.47) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL1718167 | 0.85 | LMNA (0.44) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL426376 | 0.85 | TSHR (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL30747752 | 0.85 | LMNA (0.44) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| Iodide SCHEMBL7898647 | 0.83 | TSHR (0.50) | LMNACYP2A6IDO1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019921-A1 | IODINE BIOCIDAL MATERIAL | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1996-07-04 | — | — | WO | claimed |
| US-20260117080-A1 | METAL OXIDE PARTICLES HAVING CORE/SHELL STRUCTURE HAVING UNIFORM PARTICLE SIZE DISTRIBUTION, AND METHOD FOR PRODUCING SAME | NISSAN CHEMICAL CORPORATION (JP) | 2026-04-30 | — | — | US | disclosed |
| US-12606711-B2 | Conductive stannic oxide particle-containing organic solvent-dispersed sol and method of production thereof | NISSAN CHEMICAL CORPORATION (JP) | 2026-04-21 | — | — | US | disclosed |
| US-20250256980-A1 | METAL OXIDE PARTICLE HAVING CORE-SHELL STRUCTURE AND METHOD FOR PRODUCING SAME | NISSAN CHEMICAL CORPORATION (JP) | 2025-08-14 | — | — | US | disclosed |
| US-12359039-B2 | Metal oxide particle-containing composition with reduced occurrence of volatile aldehydes | NISSAN CHEMICAL CORPORATION (JP) | 2025-07-15 | — | — | US | disclosed |
| WO-2025127152-A1 | METAL OXIDE PARTICLES HAVING IMPROVED HYDROPHOBICITY, HIGHLY CONCENTRATED METAL OXIDE SOL, AND METHODS FOR PRODUCING SAME | 日産化学株式会社 | 2025-06-19 | — | — | WO | disclosed |
| WO-2025084429-A1 | SILICA PARTICLES FOR COATING COMPOSITION AND LAMINATED SUBSTRATE | 日産化学株式会社 | 2025-04-24 | — | — | WO | disclosed |
| EP-4541769-A1 | METAL OXIDE PARTICLE HAVING CORE-SHELL STRUCTURE AND METHOD FOR PRODUCING SAME | Nissan Chemical Corporation (JP) | 2025-04-23 | — | — | EP | disclosed |
| WO-2025069657-A1 | METAL OXIDE PARTICLES WITH COATING AND VARNISH USING SAME | 日産化学株式会社 | 2025-04-03 | — | — | WO | disclosed |
| US-20250109302-A1 | CONDUCTIVE STANNIC OXIDE PARTICLE-CONTAINING ORGANIC SOLVENT-DISPERSED SOL AND METHOD OF PRODUCTION THEREOF | NISSAN CHEMICAL CORPORATION (JP) | 2025-04-03 | — | — | US | disclosed |
| US-6509125-B1 | Colored layers containing a dye-bonded polymer | TOPPAN PRINTING CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| WO-1996019921-A1 | IODINE BIOCIDAL MATERIAL | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1996-07-04 | — | — | WO | disclosed |
| US-4182764-A | DIURETIC, URICOSURIC | MERCK & CO., INC. (US) | 1980-01-08 | — | — | US | disclosed |
| US-4177285-A | DIURETICS, HYPOTENSIVES | MERCK & CO., INC. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4107329-A | Fluorinated compounds as therapeutics | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-15 | — | — | US | disclosed |
| US-4096267-A | (1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio) alkanoic acids, and derivatives thereof | MERCK & CO., INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4006180-A | DIURETIC | MERCK & CO., INC. (US) | 1977-02-01 | — | — | US | disclosed |
| US-3974212-A | DIURETIC, SALURETIC, URICOSURIC | MERCK & CO., INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3966966-A | DIURETICS | MERCK & CO., INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3944498-A | Germicidal detergent containing a thienyliodonium salt | THE DOW CHEMICAL COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260117080-A1 | METAL OXIDE PARTICLES HAVING CORE/SHELL STRUCTURE HAVING UNIFORM PARTICLE SIZE DISTRIBUTION, AND METHOD FOR PRODUCING SAME | CD63, SLC39A3, ZRANB2 | LMNA 2902/4885CYP2A6 4132/4885IDO1 609/4885 |
| US-12606711-B2 | Conductive stannic oxide particle-containing organic solvent-dispersed sol and method of production thereof | SCO2, SOD1, SPOP | LMNA 954/4885CYP2A6 4280/4885IDO1 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.