SCHEMBL426376

SCHEMBL426376

Clc1ccc([I+]c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
CYP1A2 P05177 1/20 0.50
LMNA P02545 2/20 0.44
CYP2A6 P11509 1/20 0.44
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ORAI1 Q96D31 1/20 0.41
ORAI2 Q96SN7 1/20 0.41
ORAI3 Q9BRQ5 1/20 0.41
TRPV6 Q9H1D0 1/20 0.41
KDM1A O60341 2/20 0.40
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11777482 0.97 TSHR (0.50) TSHRCYP1A2LMNACYP2A6CES2
Iodide SCHEMBL7898647 0.97 TSHR (0.50) TSHRCYP1A2LMNACYP2A6CES2
SCHEMBL5421594 0.91 CYP1A2 (0.48) TSHRCYP1A2LMNACYP2A6CES2
SCHEMBL147327 0.88 LMNA (0.57) TSHRCYP1A2LMNACYP2A6CES2
Bromide SCHEMBL11745160 0.85 LMNA (0.53) TSHRCYP1A2LMNACYP2A6CES2
Iodide SCHEMBL29644490 0.85 LMNA (0.53) TSHRCYP1A2LMNACYP2A6CES2
Hydrochloric Acid SCHEMBL1717049 0.85 LMNA (0.53) TSHRCYP1A2LMNACYP2A6CES2
SCHEMBL12762155 0.85 ALDH1A1 (0.38) TSHRCYP1A2LMNACYP2A6KDM1A
SCHEMBL36560 0.82 ALDH1A1 (0.40) TSHRCYP1A2LMNACYP2A6KDM1A
Fluoride SCHEMBL4074823 0.80 LMNA (0.47) TSHRCYP1A2LMNACYP2A6CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11914294-B2 Positive resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-02-27 US disclosed
US-20240027903-A1 Resist Material And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20240027909-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-11860540-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-02 US disclosed
US-20230400770-A1 Resist Underlayer Film Material, Patterning Process, And Method For Forming Resist Underlayer Film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-14 US disclosed
US-11835859-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-11835860-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-11829067-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-28 US disclosed
US-11829067-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-28 US disclosed
US-11822245-B2 Resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-21 US disclosed
US-20100063232-A1 POLYMERIZABLE SULFONIC ACID ONIUM SALT AND RESIN JSR CORPORATION (JP) 2010-03-11 US disclosed
US-20100040977-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-18 US disclosed
US-20090291390-A1 Acid generating agent for chemically amplified resist compositions KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2009-11-26 US disclosed
US-20090234155-A1 Acid generating agent for chemically amplified resist compositions KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2009-09-17 US disclosed
US-20070054214-A1 Acid generators, sulfonic acids, sulfonyl halides, and radiation sensitive resin compositions JSR CORPORATION (JP) 2007-03-08 US disclosed
EP-0302610-A2 Light sensitive element MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-02-08 EP disclosed
EP-0061898-B1 VISIBLE LIGHT SENSITIVE, THERMALLY DEVELOPABLE IMAGING SYSTEMS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-06-19 EP disclosed
US-4460677-A Visible light sensitive, thermally developable imaging systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-17 US disclosed
US-4386154-A ACYLATED LEUCO DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-05-31 US disclosed
EP-0061898-A1 Visible light sensitive, thermally developable imaging systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063232-A1 POLYMERIZABLE SULFONIC ACID ONIUM SALT AND RESIN ASIC1, RER1, RPS10 TSHR 941/4885CYP1A2 3868/4885LMNA 2641/4885
US-20090291390-A1 Acid generating agent for chemically amplified resist compositions ABCC1, CBR1, ARSA TSHR 2103/4885CYP1A2 852/4885LMNA 2657/4885
US-20240027903-A1 Resist Material And Patterning Process LBR, HNRNPU, EWSR1 TSHR 2364/4885CYP1A2 4438/4885LMNA 1159/4885
US-20090234155-A1 Acid generating agent for chemically amplified resist compositions POLM, CBR1, PFAS TSHR 2995/4885CYP1A2 1117/4885LMNA 578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.