Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | PPIA | P62937 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522564 | 0.86 | HTT (0.62) | HTTPPIAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23423499 | 0.82 | HTT (0.57) | HTTMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL17181733 | 0.78 | MAPT (0.45) | HTTPPIAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1522864 | 0.76 | HTT (0.57) | HTTPPIAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2858512 | 0.76 | TRPV1 (0.51) | HTTMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2027844 | 0.75 | L3MBTL1 (0.55) | HTTPPIAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8689929 | 0.75 | LMNA (0.69) | HTTMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL10064144 | 0.75 | HTT (0.56) | HTTPPIAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2026562 | 0.75 | ALDH1A1 (0.50) | HTTMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL2087947 | 0.74 | HTT (0.56) | HTTPPIAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935221-B1 | QUINOLONE DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2018-02-07 | — | — | EP | disclosed |
| US-9394300-B2 | Quinolone derivatives | CADILA HEALTHCARE LIMITED (IN) | 2016-07-19 | — | — | US | disclosed |
| US-20150299193-A1 | NOVEL QUINOLONE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299193-A1 | NOVEL QUINOLONE DERIVATIVES | NQO2, UGT1A1, CYP11B2 | HTT 1850/4885PPIA 1613/4885MAPT 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.