Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.68 |
| ▸ | BCHE | P06276 | 4/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | BRD4 | O60885 | 3/20 | 0.57 |
| ▸ | BRD2 | P25440 | 2/20 | 0.57 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.57 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17193743 | 0.99 | BCHE (0.70) | ACHEBCHEABCB1MAOAMAOB | |
| SCHEMBL19129535 | 0.92 | ACHE (0.63) | ACHEBCHEABCB1MAOAMAOB | |
| SCHEMBL17185545 | 0.92 | ABCB1 (0.65) | ACHEBCHEABCB1MAOAMAOB | |
| SCHEMBL17185531 | 0.91 | BCHE (0.71) | ACHEBCHEABCB1MAOAMAOB | |
| SCHEMBL19129478 | 0.91 | ACHE (0.64) | ACHEBCHEABCB1MAOAMAOB | |
| SCHEMBL17185547 | 0.88 | BCHE (0.68) | ACHEBCHEABCB1MAOAMAOB | |
| SCHEMBL17185553 | 0.85 | ABCB1 (0.61) | ACHEBCHEABCB1MAOAMAOB | |
| SCHEMBL23259591 | 0.85 | ACHE (0.59) | ACHEBCHEHRH3 | |
| SCHEMBL30026087 | 0.85 | ACHE (0.59) | ACHEBCHEHRH3 | |
| SCHEMBL19129507 | 0.84 | MAOA (0.56) | ACHEBCHEABCB1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868715-B2 | Apigenin analogs, compositions, and methods related thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMS (US) | 2018-01-16 | — | — | US | claimed |
| US-20170204078-A1 | APIGENIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-07-20 | — | — | US | claimed |
| WO-2015161309-A1 | APIGENIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | ZHOU JIA (US) | 2015-10-22 | — | — | WO | claimed |
| US-9868715-B2 | Apigenin analogs, compositions, and methods related thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMS (US) | 2018-01-16 | — | — | US | disclosed |
| US-9868715-B2 | Apigenin analogs, compositions, and methods related thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMS (US) | 2018-01-16 | — | — | US | disclosed |
| US-20170204078-A1 | APIGENIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170204078-A1 | APIGENIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-07-20 | — | — | US | disclosed |
| WO-2015161309-A1 | APIGENIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | ZHOU JIA (US) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015161309-A1 | APIGENIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | ZHOU JIA (US) | 2015-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204078-A1 | APIGENIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | CBS, CTH, PTGIS | ACHE 218/4885BCHE 142/4885ABCB1 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.