Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FHIT | P49789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10999244 | 0.81 | HSD17B10 (0.32) | ALDH1A1MAPTTSHRKMT2AHSD17B10 | |
| SCHEMBL13267825 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GAAMAPTSMN1; SMN2HPGD | |
| SCHEMBL3455790 | 0.72 | LMNA (0.44) | ALDH1A1GAAMAPTSMN1; SMN2HPGD | |
| SCHEMBL17451054 | 0.71 | CYP1A2 (0.40) | ALDH1A1GAAMAPTSMN1; SMN2HPGD | |
| SCHEMBL4910405 | 0.70 | NFKB1 (0.44) | ALDH1A1GAAMAPTHPGDMAOA | |
| SCHEMBL9621965 | 0.70 | NFKB1 (0.44) | ALDH1A1GAAMAPTHPGDMAOA | |
| SCHEMBL9031305 | 0.67 | TSHR (0.41) | ALDH1A1GAAMAPTSMN1; SMN2HPGD | |
| SCHEMBL23622820 | 0.66 | OAT (0.57) | ALDH1A1GAAMAPTSMN1; SMN2HPGD | |
| SCHEMBL23622662 | 0.66 | OAT (0.57) | ALDH1A1GAAMAPTSMN1; SMN2HPGD | |
| SCHEMBL23622825 | 0.66 | OAT (0.57) | ALDH1A1GAAMAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9161922-B2 | Amine oxidase inhibitors | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-10-20 | — | — | US | disclosed |