Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621965 | 1.00 | NFKB1 (0.44) | NFKB1NFKB2RELAABCB1ALDH1A1 | |
| SCHEMBL18045102 | 0.87 | NFKB1 (0.48) | NFKB1NFKB2RELAKMT2AGAA | |
| SCHEMBL18045101 | 0.87 | NFKB1 (0.48) | NFKB1NFKB2RELAKMT2AGAA | |
| SCHEMBL4906932 | 0.82 | NFKB1 (0.49) | NFKB1NFKB2RELAKMT2AGAA | |
| SCHEMBL4906940 | 0.82 | NFKB1 (0.49) | NFKB1NFKB2RELAKMT2AGAA | |
| SCHEMBL28596171 | 0.72 | NFKB1 (0.47) | NFKB1NFKB2RELAALDH1A1MEN1 | |
| SCHEMBL15424788 | 0.72 | NFKB1 (0.50) | NFKB1NFKB2RELAABCB1ALDH1A1 | |
| SCHEMBL15471468 | 0.72 | NFKB1 (0.50) | NFKB1NFKB2RELAABCB1ALDH1A1 | |
| SCHEMBL17188583 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ATSHRGAA | |
| SCHEMBL13267825 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073966-B2 | Inhibition of sweat malodor | FIRMENICH SA (CH) | 2015-07-07 | — | — | US | disclosed |
| US-20120244098-A1 | INHIBITION OF SWEAT MALODOR | FIRMENICH SA (CH) | 2012-09-27 | — | — | US | disclosed |
| EP-1846436-B1 | INHIBITION OF SWEAT MALODOUR | FIRMENICH & CIE (CH) | 2012-09-12 | — | — | EP | disclosed |
| US-8206692-B2 | Inhibition of sweat malodor | FIRMENICH SA (CH) | 2012-06-26 | — | — | US | disclosed |
| US-20080025935-A1 | INHIBITION OF SWEAT MALODOR | FIRMENICH SA (CH) | 2008-01-31 | — | — | US | disclosed |
| EP-1846436-A2 | INHIBITION OF SWEAT MALODOUR | Firmenich S.A. (CH) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006079934-A2 | INHIBITION OF SWEAT MALODOUR | FIRMENICH SA (CH) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120244098-A1 | INHIBITION OF SWEAT MALODOR | SQOR, MAL2, TST | NFKB1 3041/4885NFKB2 2595/4885RELA 2691/4885 |
| US-20080025935-A1 | INHIBITION OF SWEAT MALODOR | MAL2, SQOR, TST | NFKB1 3174/4885NFKB2 2738/4885RELA 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.