Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17192805 | 0.83 | MEN1 (0.33) | CYP2D6CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL17192814 | 0.83 | ESR1 (0.36) | CYP2D6CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL8459305 | 0.82 | GABRA1 (0.41) | CYP2D6CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL29101876 | 0.82 | GABRA1 (0.41) | CYP2D6CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL29101886 | 0.78 | ALDH1A1 (0.38) | CYP2D6CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL4326158 | 0.77 | CYP2D6 (0.46) | CYP2D6CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL8520457 | 0.76 | GABRA1 (0.42) | CYP2D6CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL8651209 | 0.76 | LMNA (0.36) | CYP2D6CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL9275411 | 0.76 | HPGD (0.39) | CYP2D6CYP2C19KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9838496 | 0.76 | TAAR1 (0.46) | CYP2D6CYP2C19KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150299146-A1 | TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299146-A1 | TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF | RTN3, CYCS, ATL3 | CYP2D6 632/4885CYP2C19 184/4885KDM4E 2748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.