Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21089018 | 0.87 | ALOX5 (0.32) | CNR2 | |
| SCHEMBL17177771 | 0.83 | PDE10A (0.33) | CNR2GPR119KIF18A | |
| SCHEMBL17196425 | 0.72 | HRH4 (0.36) | — | |
| SCHEMBL16511461 | 0.69 | ALDH1A1 (0.45) | — | |
| SCHEMBL17196402 | 0.69 | S100A9 (0.32) | — | |
| SCHEMBL17196389 | 0.67 | HTT (0.37) | — | |
| SCHEMBL17196466 | 0.66 | LRRK2 (0.38) | — | |
| SCHEMBL24587389 | 0.63 | NR1H2 (0.37) | CNR2 | |
| SCHEMBL17173648 | 0.63 | PTGS2 (0.37) | GPR119KIF18A | |
| SCHEMBL17177764 | 0.62 | HRH4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015158427-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | Grünenthal GmbH (DE) | 2015-10-22 | — | — | WO | disclosed |