Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17196470 | 0.87 | CNR2 (0.33) | CNR2 | |
| SCHEMBL17177771 | 0.79 | PDE10A (0.33) | PTGS2CNR2 | |
| SCHEMBL21089051 | 0.73 | ALDH1A1 (0.42) | ALOX5PTGS1PTGS2 | |
| SCHEMBL21089255 | 0.69 | CTSS (0.36) | ALOX5NPC1RAB9A | |
| SCHEMBL17196425 | 0.62 | HRH4 (0.36) | PTGS1PTGS2 | |
| SCHEMBL21089369 | 0.61 | APLNR (0.34) | — | |
| SCHEMBL16511461 | 0.60 | ALDH1A1 (0.45) | PTGS1PTGS2NPC1 | |
| SCHEMBL24587389 | 0.60 | NR1H2 (0.37) | CNR2 | |
| SCHEMBL17173648 | 0.60 | PTGS2 (0.37) | PTGS1PTGS2 | |
| SCHEMBL21653458 | 0.60 | TDP1 (0.44) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495360-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | Grünenthal GmbH (DE) | 2019-06-12 | — | — | EP | disclosed |