Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17197316 | 1.00 | ADRB1 (0.47) | ADRB1MTNR1AMTNR1BKMT2AMEN1 | |
| SCHEMBL928382 | 0.83 | GPR119 (0.53) | MTNR1AMTNR1BKMT2AMEN1ALDH1A1 | |
| SCHEMBL19710919 | 0.82 | NOTUM (0.52) | ADRB1HTR7HCRTR1HCRTR2ALDH1A1 | |
| Oxalic Acid SCHEMBL22721188 | 0.82 | HTR7 (0.47) | ADRB1MTNR1AMTNR1BKMT2AHTR7 | |
| SCHEMBL8321177 | 0.81 | KMT2A (0.63) | ADRB1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL22721145 | 0.80 | ADRB1 (0.53) | ADRB1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL26256380 | 0.80 | ALDH1A1 (0.56) | ADRB1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL18711481 | 0.80 | USP2 (0.53) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19710858 | 0.79 | MGLL (0.43) | CYP1A2HTR7HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL19702012 | 0.79 | NOTUM (0.55) | CYP1A2HCRTR1HCRTR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015158310-A1 | TYROSINE KINASE INHIBITOR AND USES THEREOF | 山东轩竹医药科技有限公司 | 2015-10-22 | — | — | WO | disclosed |