SCHEMBL17199700

SCHEMBL17199700

Brc1ccc2c(c1)C(=Cc1ccccc1C=C1c3cc(Br)ccc3-c3ccc(Br)cc31)c1cc(Br)ccc1-2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.48
S100A4 P26447 1/20 0.45
BAX Q07812 2/20 0.40
AHR P35869 1/20 0.38
CYP2A6 P11509 1/20 0.37
LCK P06239 1/20 0.37
APP P05067 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
BCL2 P10415 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
MCL1 Q07820 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1242518 0.82 PTPRC (0.47) PTPRCS100A4LCKAPPCYP1A2
SCHEMBL9177130 0.79 CYP19A1 (0.48) PTPRCS100A4LCKAPPCYP1A2
SCHEMBL9177137 0.79 CYP19A1 (0.48) PTPRCS100A4LCKAPPCYP1A2
SCHEMBL17199708 0.78 S100A4 (0.48) PTPRCS100A4LCKAPPBCL2
SCHEMBL17199713 0.78 LCK (0.50) PTPRCS100A4LCKAPPBCL2
SCHEMBL17199715 0.78 S100A4 (0.43) PTPRCS100A4LCKAPPCYP1A2
SCHEMBL14506937 0.77 PTPRC (0.43) PTPRCS100A4CYP2A6LCKAPP
SCHEMBL14506934 0.76 AMY1A (0.42) PTPRCS100A4CYP2A6LCKBCL2
SCHEMBL7866191 0.74 PTPRC (0.70) PTPRCS100A4AHRCYP2A6BCL2
SCHEMBL26112719 0.74 PTPRC (0.70) PTPRCS100A4AHRCYP2A6BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015161989-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2015-10-29 WO disclosed
WO-2015161989-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2015-10-29 WO disclosed
EP-2937399-A1 Hole-transport materials for organic solar cells or organic optical sensors BASF SE (DE) 2015-10-28 EP disclosed
EP-2937399-A1 Hole-transport materials for organic solar cells or organic optical sensors BASF SE (DE) 2015-10-28 EP disclosed