SCHEMBL1242570

SCHEMBL1242570

FC(F)(F)c1cc(C=C2c3cc(Br)ccc3-c3ccc(Br)cc32)cc(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.41
S100A4 P26447 1/20 0.37
TMPRSS4 Q9NRS4 1/20 0.35
PTPRC P08575 1/20 0.33
KCNMA1 Q12791 1/20 0.33
MAP1LC3B Q9GZQ8 1/20 0.33
PTPN2 P17706 1/20 0.32
PTPN1 P18031 1/20 0.32
PTPN6 P29350 1/20 0.32
PPARG P37231 1/20 0.32
SLC6A4 P31645 1/20 0.32
PLK4 O00444 2/20 0.31
PDK2 Q15119 1/20 0.31
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31
RXRA P19793 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
BCL2 P10415 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17199713 0.82 LCK (0.50) LCKS100A4PTPRCMAP1LC3BPLK4
SCHEMBL17199708 0.78 S100A4 (0.48) LCKS100A4PTPRCPLK4MEN1
SCHEMBL1242518 0.73 PTPRC (0.47) LCKS100A4PTPRCMEN1KMT2A
SCHEMBL17199715 0.73 S100A4 (0.43) LCKS100A4PTPRCPPARGPLK4
SCHEMBL9177130 0.70 CYP19A1 (0.48) LCKS100A4PTPRCMEN1KMT2A
SCHEMBL9177137 0.70 CYP19A1 (0.48) LCKS100A4PTPRCMEN1KMT2A
SCHEMBL17199705 0.69 LCK (0.40) LCKS100A4PTPRCPLK4MEN1
SCHEMBL4166283 0.69 NR3C1 (0.44) SLC6A4IDO1TDO2
SCHEMBL15164208 0.68 ALDH1A1 (0.40) LCKMEN1KMT2A
SCHEMBL17199700 0.67 PTPRC (0.48) LCKS100A4PTPRCBCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1832616-B1 Pi-conjugated polymer RICOH CO LTD (JP) 2012-10-24 EP disclosed
US-7893192-B2 Pi-conjugated polymer RICOH COMPANY, LTD. (JP) 2011-02-22 US disclosed
US-7893192-B2 Pi-conjugated polymer RICOH COMPANY, LTD. (JP) 2011-02-22 US disclosed
US-7893192-B2 Pi-conjugated polymer RICOH COMPANY, LTD. (JP) 2011-02-22 US disclosed
US-20070213503-A1 PI-CONJUGATED POLYMER RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070213503-A1 PI-CONJUGATED POLYMER RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070213503-A1 PI-CONJUGATED POLYMER RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
EP-1832616-A1 Pi-conjugated polymer Ricoh Company, Ltd. (JP) 2007-09-12 EP disclosed