Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | HTR1A | P08908 | 5/20 | 0.37 |
| ▸ | HTR7 | P34969 | 5/20 | 0.37 |
| ▸ | HTR1D | P28221 | 4/20 | 0.37 |
| ▸ | HTR1B | P28222 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | HTR5A | P47898 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATP4A | P20648 | 2/20 | 0.36 |
| ▸ | ATP4B | P51164 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199829 | 0.97 | HTR2C (0.38) | HTR2CHTR1AHTR7HTR1DHTR1B | |
| SCHEMBL17212363 | 0.81 | MAPT (0.41) | HTR2CALDH1A1ATP4AATP4BMAPT | |
| Hydrochloric Acid SCHEMBL17200831 | 0.80 | ALDH1A1 (0.39) | HTR2CHTR1AHTR7HTR1DHTR1B | |
| SCHEMBL28181208 | 0.78 | MGLL (0.47) | HTR2CHTR1AHTR7HTR1DHTR1B | |
| SCHEMBL19058878 | 0.78 | ALDH1A1 (0.38) | HTR2CHTR1AHTR7HTR1DHTR1B | |
| SCHEMBL17212359 | 0.77 | ALDH1A1 (0.37) | HTR2CHTR1AHTR7HTR1DHTR1B | |
| SCHEMBL17199827 | 0.77 | ALDH1A1 (0.41) | HTR2CHTR1AHTR7HTR1DHTR1B | |
| SCHEMBL17529687 | 0.76 | CA1 (0.46) | HTR2CALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL17212360 | 0.75 | JAK2 (0.43) | HTR2CHTR1AHTR7HTR1DHTR1B | |
| SCHEMBL27872644 | 0.75 | NFE2L2 (0.42) | ALDH1A1MAPTMEN1KMT2AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416148-B2 | Phosphorus compound and transition metal complex of the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2016-08-16 | — | — | US | disclosed |
| US-20150307531-A1 | PHOSPHORUS COMPOUND AND TRANSITION METAL COMPLEX OF THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307531-A1 | PHOSPHORUS COMPOUND AND TRANSITION METAL COMPLEX OF THE SAME | P2RY10, PTH1R, INPP5A | HTR2C 4670/4885HTR1A 4095/4885HTR7 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.