Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17201753 | 1.00 | CYP19A1 (0.58) | CYP19A1PTGS2ALOX5PTGS1APP | |
| SCHEMBL29987008 | 1.00 | CYP19A1 (0.58) | CYP19A1PTGS2ALOX5PTGS1APP | |
| SCHEMBL17201734 | 0.93 | TTR (0.58) | CYP19A1PTGS2ALOX5PTGS1APP | |
| SCHEMBL17201735 | 0.93 | TTR (0.58) | CYP19A1PTGS2ALOX5PTGS1APP | |
| SCHEMBL30279751 | 0.93 | TTR (0.58) | CYP19A1PTGS2ALOX5PTGS1APP | |
| SCHEMBL30279755 | 0.90 | CYP19A1 (0.52) | CYP19A1PTGS2ALOX5PTGS1APP | |
| SCHEMBL28917374 | 0.90 | CYP19A1 (0.52) | CYP19A1PTGS2ALOX5PTGS1APP | |
| SCHEMBL25614436 | 0.90 | CYP19A1 (0.52) | CYP19A1PTGS2ALOX5PTGS1APP | |
| SCHEMBL17201740 | 0.89 | MAOA (0.61) | CYP19A1PTGS2ALOX5PTGS1MAOA | |
| SCHEMBL13824957 | 0.89 | MAOA (0.61) | CYP19A1PTGS2ALOX5PTGS1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352310-B2 | Prenylated hydroxystilbenes | Kynan Duke IP, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| US-11352310-B2 | Prenylated hydroxystilbenes | Kynan Duke IP, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| EP-2709975-B1 | PRENYLATED HYDROXYSTILBENES | KYNAN DUKE IP LLC (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-2709975-B1 | PRENYLATED HYDROXYSTILBENES | KYNAN DUKE IP LLC (US) | 2022-01-12 | — | — | EP | disclosed |
| US-20200331833-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2020-10-22 | — | — | US | disclosed |
| US-20200331833-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2020-10-22 | — | — | US | disclosed |
| CN-107266297-B | Prenylated hydroxystilbenes, pharmaceutical compositions containing the same, use and preparation method thereof | 悉尼大学 | 2020-10-16 | — | — | CN | disclosed |
| US-10696615-B2 | Prenylated hydroxystilbenes | THE UNIVERSITY OF SYDNEY (AU) | 2020-06-30 | — | — | US | disclosed |
| US-10696615-B2 | Prenylated hydroxystilbenes | THE UNIVERSITY OF SYDNEY (AU) | 2020-06-30 | — | — | US | disclosed |
| US-20190194105-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2019-06-27 | — | — | US | disclosed |
| US-20190194105-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2019-06-27 | — | — | US | disclosed |
| US-10196335-B2 | Prenylated hydroxystilbenes | THE UNIVERSITY OF SYDNEY (AU) | 2019-02-05 | — | — | US | disclosed |
| US-10196335-B2 | Prenylated hydroxystilbenes | THE UNIVERSITY OF SYDNEY (AU) | 2019-02-05 | — | — | US | disclosed |
| US-20150307429-A1 | PRENYLATED HYDROXYSTILBENES | Kynan Duke IP, LLC | 2015-10-29 | — | — | US | disclosed |
| US-20150307429-A1 | PRENYLATED HYDROXYSTILBENES | Kynan Duke IP, LLC | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196335-B2 | Prenylated hydroxystilbenes | HMGB2, CYP51A1, CYP8B1 | CYP19A1 212/4885PTGS2 324/4885ALOX5 418/4885 |
| US-20200331833-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, HSD3B1, CYP8B1 | CYP19A1 64/4885PTGS2 1767/4885ALOX5 1677/4885 |
| US-20150307429-A1 | PRENYLATED HYDROXYSTILBENES | HMGB2, CYP51A1, CYP8B1 | CYP19A1 212/4885PTGS2 324/4885ALOX5 418/4885 |
| US-10696615-B2 | Prenylated hydroxystilbenes | HSD11B1, CYP8B1, NR1H2 | CYP19A1 79/4885PTGS2 807/4885ALOX5 2768/4885 |
| US-11352310-B2 | Prenylated hydroxystilbenes | HSD11B1, HSD3B1, CYP8B1 | CYP19A1 64/4885PTGS2 1767/4885ALOX5 1677/4885 |
| US-20190194105-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, CYP8B1, NR1H2 | CYP19A1 79/4885PTGS2 807/4885ALOX5 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.