Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844922 | 0.86 | HTR6 (0.62) | HTR6 | |
| SCHEMBL18553780 | 0.79 | HTR6 (0.64) | ALDH1A1HTR6KMT2AMEN1POLB | |
| SCHEMBL29978507 | 0.75 | GFER (0.48) | ALDH1A1TP53TDP1KMT2AALPL | |
| SCHEMBL23043636 | 0.75 | GFER (0.48) | ALDH1A1TP53TDP1KMT2AALPL | |
| SCHEMBL28211335 | 0.75 | RYR2 (0.50) | ALDH1A1TP53TDP1KMT2AMEN1 | |
| SCHEMBL15916656 | 0.74 | KMT2A (0.70) | ALDH1A1TP53TDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28210781 | 0.74 | RYR2 (0.49) | ALDH1A1TP53TDP1KMT2AMEN1 | |
| SCHEMBL18553769 | 0.74 | HTR6 (0.54) | ALDH1A1HTR6KMT2AMEN1HTT | |
| SCHEMBL112712 | 0.73 | ALDH1A1 (0.56) | ALDH1A1TDP1KMT2AMEN1KDM4E | |
| SCHEMBL31368924 | 0.72 | ALDH1A1 (1.00) | ALDH1A1TP53TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307501-A1 | Compositions and Methods for the Treatment of Metabolic and Related Disorders | BAYLOR COLLEGE OF MEDICINE (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307501-A1 | Compositions and Methods for the Treatment of Metabolic and Related Disorders | FABP4, LIPC, PC | ALDH1A1 1331/4885TP53 3474/4885TDP1 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.