Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.42 |
| ▸ | SCD | O00767 | 6/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686174 | 0.78 | ADORA2B (0.66) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2687202 | 0.78 | ADORA2B (0.51) | ADORA3ADORA2AADORA2BADORA1PLK4 | |
| SCHEMBL1720374 | 0.77 | STIM1 (0.43) | ADORA3ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL4016921 | 0.76 | ADORA2B (0.41) | ADORA3ADORA2AADORA2BADORA1PLK4 | |
| SCHEMBL1727143 | 0.75 | ADORA2B (0.41) | ADORA3ADORA2AADORA2BSCDADORA1 | |
| SCHEMBL1720580 | 0.74 | SCD (0.38) | ADORA3ADORA2AADORA2BSCDADORA1 | |
| SCHEMBL1724494 | 0.74 | ADORA2B (0.46) | ADORA3ADORA2AADORA2BSCDADORA1 | |
| SCHEMBL1720327 | 0.72 | EGFR (0.38) | ADORA3ADORA2AADORA2BSCDEGFR | |
| SCHEMBL15642798 | 0.71 | ADORA1 (0.40) | ADORA3ADORA2AADORA2BADORA1GRIN1 | |
| SCHEMBL4019325 | 0.68 | LMNA (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405917-A2 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS | Advinus Therapeutics Private Limited (IN) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103547-A2 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2010-09-16 | — | — | WO | disclosed |