Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 7/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720825 | 0.90 | STIM1 (0.43) | CCNT1 | |
| SCHEMBL1727143 | 0.88 | ADORA2B (0.41) | SCDEGFRKCNN3ADORA3ADORA2A | |
| SCHEMBL2687202 | 0.77 | ADORA2B (0.51) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL1720325 | 0.74 | ADORA3 (0.42) | SCDEGFRADORA3ADORA2AADORA2B | |
| SCHEMBL2686174 | 0.73 | ADORA2B (0.66) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL1721091 | 0.69 | ADORA1 (0.43) | ADORA2AADORA2BADORA1GRIN1GRIN2B | |
| SCHEMBL1724494 | 0.68 | ADORA2B (0.46) | SCDADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2686641 | 0.66 | ADORA2B (0.49) | ADORA3ADORA2AADORA2BADORA1CCNT1 | |
| SCHEMBL1865267 | 0.65 | ADORA1 (0.44) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL1721383 | 0.64 | ADORA2B (0.37) | ADORA2BADORA1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727391-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CANCER | Impetis Biosciences Ltd. (IN) | 2020-10-28 | — | — | EP | claimed |
| EP-3727391-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CANCER | Impetis Biosciences Ltd. (IN) | 2020-10-28 | — | — | EP | disclosed |
| EP-2405917-A2 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS | Advinus Therapeutics Private Limited (IN) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103547-A2 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2010-09-16 | — | — | WO | disclosed |