Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | TPH1 | P17752 | 1/20 | 0.35 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016921 | 0.92 | ADORA2B (0.41) | LMNAHTTPARP1NR3C1TPH1 | |
| SCHEMBL4295147 | 0.88 | MAOB (0.40) | LMNAHTTGAASMN1; SMN2PARP1 | |
| SCHEMBL4018480 | 0.78 | TPH1 (0.50) | HTTKDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL4016181 | 0.76 | MEN1 (0.42) | LMNAHTTALDH1A1HPGD | |
| SCHEMBL5509419 | 0.74 | ADORA3 (0.44) | LMNAHTTKDM4EALDH1A1GAA | |
| SCHEMBL4014400 | 0.73 | ADORA2A (0.41) | PARP1 | |
| SCHEMBL4284406 | 0.73 | NOD1 (0.39) | LMNAHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5061625 | 0.73 | TPH1 (0.48) | HTTKDM4EALDH1A1SMN1; SMN2TPH1 | |
| SCHEMBL4016371 | 0.68 | ADORA2B (0.64) | — | |
| SCHEMBL1720325 | 0.68 | ADORA3 (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009088518-A1 | A2B ADENOSINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF CANCER | CV THERAPEUTICS, INC. (US) | 2009-07-16 | — | — | WO | disclosed |