Lactic Acid

Lactic Acid

SCHEMBL1720340

CC(O)C(=O)O.CCOc1c(N)c(N)cc2nc3ccccc3cc12

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1

The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
KDM4E B2RXH2 4/20 0.51
KMT2A Q03164 3/20 0.51
HPGD P15428 3/20 0.51
MEN1 O00255 2/20 0.51
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
CASP1 P29466 1/20 0.51
CASP7 P55210 1/20 0.51
HSD17B10 Q99714 1/20 0.51
TLR8 Q9NR97 5/20 0.42
GAA P10253 3/20 0.41
LMNA P02545 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
GLA P06280 1/20 0.41
POLB P06746 1/20 0.41
PTBP1 P26599 1/20 0.41
RCE1 Q9Y256 1/20 0.41
FDPS P14324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactic Acid SCHEMBL9542498 0.91 ALDH1A1 (0.53) ALDH1A1KDM4EKMT2AHPGDMEN1
Lactic Acid SCHEMBL6898755 0.90 ALDH1A1 (0.53) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL10777929 0.88 TLR8 (0.52) ALDH1A1KDM4EKMT2AHPGDMEN1
Lactic Acid SCHEMBL6283358 0.83 KDM4E (0.54) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL10433566 0.78 TLR8 (0.52) ALDH1A1KDM4EKMT2AHPGDMEN1
SCHEMBL11761449 0.73 TLR8 (0.40) ALDH1A1KDM4EKMT2AHPGDMEN1
Acridine SCHEMBL10926258 0.73 ALDH1A1 (0.58) ALDH1A1KDM4EKMT2AHPGDMEN1
Lactic Acid SCHEMBL5515418 0.73 ALDH1A1 (0.44) ALDH1A1KDM4EKMT2AHPGDMEN1
Lactic Acid SCHEMBL28885529 0.72 ALDH1A1 (0.43) ALDH1A1KDM4EKMT2AHPGDMEN1
Lactic Acid SCHEMBL1720338 0.71 TLR8 (0.45) ALDH1A1KDM4EKMT2AHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020115026-A1 Silver halide material for optical memory devices with luminescent reading and methods for the treatment thereof D DATA INC 2002-08-22 US claimed
US-6265140-B1 OXIDIZING THE SILVER PARTICLES TO FORM INSOLUBLE SALT PARTICLES IN A PRESENCE OF ANIONS TO FORM SILVER AND INSOLUBLE SILVER SALTS TRIDSTORE IP, LLC 2001-07-24 US claimed
EP-0963571-A1 SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF OMD Devices LLC (US) 1999-12-15 EP claimed
WO-1998037456-A9 SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF OMD DEVICES LLC (US) 1999-11-11 WO claimed
WO-1998037456-A1 SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF OMD DEVICES LLC (US) 1998-08-27 WO claimed
EP-1817339-B1 PURIFICATION OF RECOMBINANT HUMAN FACTOR XIII ZYMOGENETICS INC (US) 2012-01-11 EP disclosed
US-6960426-B2 Silver halide material for optical memory devices with luminescent reading and methods for the treatment thereof D DATA INC. (US) 2005-11-01 US disclosed
US-20020115026-A1 Silver halide material for optical memory devices with luminescent reading and methods for the treatment thereof D DATA INC 2002-08-22 US disclosed
US-6265140-B1 OXIDIZING THE SILVER PARTICLES TO FORM INSOLUBLE SALT PARTICLES IN A PRESENCE OF ANIONS TO FORM SILVER AND INSOLUBLE SILVER SALTS TRIDSTORE IP, LLC 2001-07-24 US disclosed
EP-0963571-A1 SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF OMD Devices LLC (US) 1999-12-15 EP disclosed
WO-1998037456-A9 SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF OMD DEVICES LLC (US) 1999-11-11 WO disclosed
WO-1998037456-A1 SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF OMD DEVICES LLC (US) 1998-08-27 WO disclosed
US-5204447-A Precipitating by adjustment of pH to 5.5 to 6.5, recovering ZYMOGENETICS, INC. (US) 1993-04-20 US disclosed
WO-1993003147-A1 PURIFICATION OF FACTOR XIII ZYMOGENETICS, INC. (US) 1993-02-18 WO disclosed
EP-0442964-A1 PURIFICATION OF FACTOR XIII ZYMOGENETICS, INC. (US) 1991-08-28 EP disclosed
WO-1990005777-A1 PURIFICATION OF FACTOR XIII ZYMOGENETICS, INC. (US) 1990-05-31 WO disclosed
EP-0037078-B1 PROCESS FOR HEAT TREATMENT OF AQUEOUS SOLUTION CONTAINING HUMAN BLOOD COAGULATION FACTOR XIII GREEN CROSS CORPORATION (JP) 1984-03-14 EP disclosed
US-3931399-A MULTISTAGE FROM EXTRACTION OF HUMAN PLACENTAE BEHRINGWERKE AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed
US-3931399-A MULTISTAGE FROM EXTRACTION OF HUMAN PLACENTAE BEHRINGWERKE AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed
US-3904751-A Process for isolating a fibrin stabilizing factor from human placenta BEHRINGWERKE AG 1975-09-09 US disclosed