Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL9542498 | 0.85 | ALDH1A1 (0.53) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| Lactic Acid SCHEMBL6898755 | 0.84 | ALDH1A1 (0.53) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| Lactic Acid SCHEMBL1720340 | 0.83 | ALDH1A1 (0.51) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| Lactic Acid SCHEMBL11262321 | 0.75 | KDM4E (0.66) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| Lactic Acid SCHEMBL1720338 | 0.74 | TLR8 (0.45) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| Acridine SCHEMBL10926258 | 0.74 | ALDH1A1 (0.58) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| Lactic Acid SCHEMBL5515418 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| Lactic Acid SCHEMBL11334625 | 0.74 | TLR8 (0.44) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| Lactic Acid SCHEMBL28885529 | 0.73 | ALDH1A1 (0.43) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| Lactic Acid SCHEMBL11226196 | 0.72 | HSD17B10 (0.68) | KDM4EALDH1A1KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020115026-A1 | Silver halide material for optical memory devices with luminescent reading and methods for the treatment thereof | D DATA INC | 2002-08-22 | — | — | US | claimed |
| US-6265140-B1 | OXIDIZING THE SILVER PARTICLES TO FORM INSOLUBLE SALT PARTICLES IN A PRESENCE OF ANIONS TO FORM SILVER AND INSOLUBLE SILVER SALTS | TRIDSTORE IP, LLC | 2001-07-24 | — | — | US | claimed |
| EP-0963571-A1 | SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF | OMD Devices LLC (US) | 1999-12-15 | — | — | EP | claimed |
| WO-1998037456-A9 | SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF | OMD DEVICES LLC (US) | 1999-11-11 | — | — | WO | claimed |
| WO-1998037456-A1 | SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF | OMD DEVICES LLC (US) | 1998-08-27 | — | — | WO | claimed |
| US-6960426-B2 | Silver halide material for optical memory devices with luminescent reading and methods for the treatment thereof | D DATA INC. (US) | 2005-11-01 | — | — | US | disclosed |
| US-20020115026-A1 | Silver halide material for optical memory devices with luminescent reading and methods for the treatment thereof | D DATA INC | 2002-08-22 | — | — | US | disclosed |
| US-6265140-B1 | OXIDIZING THE SILVER PARTICLES TO FORM INSOLUBLE SALT PARTICLES IN A PRESENCE OF ANIONS TO FORM SILVER AND INSOLUBLE SILVER SALTS | TRIDSTORE IP, LLC | 2001-07-24 | — | — | US | disclosed |
| EP-0963571-A1 | SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF | OMD Devices LLC (US) | 1999-12-15 | — | — | EP | disclosed |
| WO-1998037456-A9 | SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF | OMD DEVICES LLC (US) | 1999-11-11 | — | — | WO | disclosed |
| WO-1998037456-A1 | SILVER HALIDE MATERIAL FOR OPTICAL MEMORY DEVICES WITH LUMINESCENT READING AND METHODS FOR THE TREATMENT THEREOF | OMD DEVICES LLC (US) | 1998-08-27 | — | — | WO | disclosed |