⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147174 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL7545108 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL1701715 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL2822938 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL7541388 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL2128896 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL1235539 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL3208419 | 0.98 | TSHR (0.64) | — | |
| SCHEMBL22500035 | 0.98 | — | — | |
| SCHEMBL7548607 | 0.98 | TSHR (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075187-B | Carbonyl pyrazole antitumor compound as well as preparation method and application thereof | 山东大学 | 2023-05-12 | — | — | CN | claimed |
| EP-3747957-A1 | FLUORESCENT VINYL TIOPHENE AND BITIOPHENE COUMARINS DYES AND METHOD OF SYNTHESIS THEREOF | Universidade de Évora (PT) | 2020-12-09 | — | — | EP | claimed |
| CN-107619407-B | Bis- target spot inhibitor of HDAC and VEGFR based on pazopanib structure and its preparation method and application | 山东大学 | 2019-05-24 | — | — | CN | claimed |
| CN-107619407-A | Double target spot inhibitor of HDAC and VEGFR based on pazopanib structure and its preparation method and application | 山东大学 | 2018-01-23 | — | — | CN | claimed |
| EP-3194538-A1 | DISPERSANT VISCOSITY MODIFIERS WITH AMINE FUNCTIONALITY | The Lubrizol Corporation (US) | 2017-07-26 | — | — | EP | claimed |
| WO-2016044254-A1 | DISPERSANT VISCOSITY MODIFIERS WITH AMINE FUNCTIONALITY | THE LUBRIZOL CORPORATION (US) | 2016-03-24 | — | — | WO | claimed |
| CN-103864793-A | Substituted purin-9-acetamino isohydroxamic acid histone deacetylase inhibitor and preparation method and application thereof | UNIV SHANDONG | 2014-06-18 | — | — | CN | claimed |
| EP-0906305-A1 | 1-(1H-PYRROL-2-YLMETHYL)-2-PIPERIDONE AS CELL MIGRATION INHIBITOR | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-04-07 | — | — | EP | claimed |
| WO-1997046552-A1 | 1-(1H-PYRROL-2-YLMETHYL)-2-PIPERIDONE AS CELL MIGRATION INHIBITOR | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-12-11 | — | — | WO | claimed |
| CN-122036735-A | Pyrazolo [3,4-d ] pyrimidine-hydroxamic acid derivatives, synthetic method and application | 云南大学 | 2026-05-15 | — | — | CN | disclosed |
| US-20260092057-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-04-02 | — | — | US | disclosed |
| EP-4712961-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| EP-4587435-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2025-07-23 | — | — | EP | disclosed |
| WO-2025132542-A1 | MACROCYCLIC OREXIN AGONISTS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-26 | — | — | WO | disclosed |
| EP-0312345-A2 | 1-(5-(4-substituted-1-piperazinyl)methyl)-pyrrol-2-yl or furan-2-yl)methyl-2-piperidinones useful in treating schizophrenia | MCNEILAB, INC. (US) | 1989-04-19 | — | — | EP | disclosed |
| CN-85101902-A | Enkephalinase inhibitor | — | 1987-01-17 | — | — | CN | disclosed |
| EP-0198271-A2 | Peptides | MERCK PATENT GmbH (DE) | 1986-10-22 | — | — | EP | disclosed |
| EP-0025370-B1 | PREPARATION OF FLUORINATED METHYLAMINOALKANOIC ACIDS, PROCESS INTERMEDIATES AND THEIR PREPARATION | MERRELL TORAUDE ET COMPAGNIE (FR) | 1983-05-11 | — | — | EP | disclosed |
| US-4353828-A | Preparation of fluorinated methyl aminoalkanoic acids and novel process intermediates | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-10-12 | — | — | US | disclosed |
| EP-0025370-A2 | Preparation of fluorinated methylaminoalkanoic acids, process intermediates and their preparation | MERRELL TORAUDE ET COMPAGNIE (FR) | 1981-03-18 | — | — | EP | disclosed |